Recent advances in the genomic resources for sheep.

IF 2.7 4区 生物学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY Mammalian Genome Pub Date : 2023-12-01 Epub Date: 2023-09-26 DOI:10.1007/s00335-023-10018-z
Shernae A Woolley, Mazdak Salavati, Emily L Clark
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Abstract

Sheep (Ovis aries) provide a vital source of protein and fibre to human populations. In coming decades, as the pressures associated with rapidly changing climates increase, breeding sheep sustainably as well as producing enough protein to feed a growing human population will pose a considerable challenge for sheep production across the globe. High quality reference genomes and other genomic resources can help to meet these challenges by: (1) informing breeding programmes by adding a priori information about the genome, (2) providing tools such as pangenomes for characterising and conserving global genetic diversity, and (3) improving our understanding of fundamental biology using the power of genomic information to link cell, tissue and whole animal scale knowledge. In this review we describe recent advances in the genomic resources available for sheep, discuss how these might help to meet future challenges for sheep production, and provide some insight into what the future might hold.

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绵羊基因组资源的最新进展。
绵羊为人类提供了重要的蛋白质和纤维来源。在未来几十年里,随着气候快速变化带来的压力增加,可持续地饲养绵羊以及生产足够的蛋白质来养活不断增长的人口,将对全球绵羊生产构成相当大的挑战。高质量的参考基因组和其他基因组资源可以通过以下方式帮助应对这些挑战:(1)通过添加有关基因组的先验信息来为育种计划提供信息;(2)提供用于表征和保护全球遗传多样性的工具,如泛基因组,组织和整个动物规模的知识。在这篇综述中,我们描述了绵羊基因组资源的最新进展,讨论了这些资源如何有助于应对绵羊生产的未来挑战,并对未来可能发生的事情提供了一些见解。
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来源期刊
Mammalian Genome
Mammalian Genome 生物-生化与分子生物学
CiteScore
4.00
自引率
0.00%
发文量
33
审稿时长
6-12 weeks
期刊介绍: Mammalian Genome focuses on the experimental, theoretical and technical aspects of genetics, genomics, epigenetics and systems biology in mouse, human and other mammalian species, with an emphasis on the relationship between genotype and phenotype, elucidation of biological and disease pathways as well as experimental aspects of interventions, therapeutics, and precision medicine. The journal aims to publish high quality original papers that present novel findings in all areas of mammalian genetic research as well as review articles on areas of topical interest. The journal will also feature commentaries and editorials to inform readers of breakthrough discoveries as well as issues of research standards, policies and ethics.
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