Description of Macrophage-Like Cells in Active Ocular Toxoplasmosis.

IF 2.6 4区 医学 Q2 OPHTHALMOLOGY Ocular Immunology and Inflammation Pub Date : 2024-10-01 Epub Date: 2023-10-03 DOI:10.1080/09273948.2023.2263073
Ester Carreño, Inés Hernanz, Beatriz Collado, Francesco Pichi
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Abstract

Macrophage-like cells (MLC) have a fundamental role in the maintenance of immunosurveillance, response to inflammation and tissue injury in the retina. MLC can be visualized in vivo with conventional en face optical coherence tomography (OCT). The aim of this study is to describe this population of cells in active toxoplasmosis. We present two cases of active toxoplasma retinochoroiditis imaged at 2 time points, where the MLC were threshold after image processing and averaging for removing background and noise. In both patients the MLC collocated with the area of ischemia at the level of the choriocapillaris and retinal vessels.

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活动性眼弓形虫中巨噬细胞样细胞的描述。
巨噬细胞样细胞(MLC)在维持免疫监测、对视网膜炎症和组织损伤的反应中发挥着重要作用。MLC可以通过传统的表面光学相干断层扫描(OCT)在体内进行可视化。本研究的目的是描述这种活跃的弓形虫细胞群。我们报告了两例在2个时间点成像的活动性弓形虫视网膜脉络膜炎,其中MLC是图像处理和平均去除背景和噪声后的阈值。在这两名患者中,MLC与绒毛膜毛细血管和视网膜血管水平的缺血区域并置。
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来源期刊
CiteScore
6.20
自引率
15.20%
发文量
285
审稿时长
6-12 weeks
期刊介绍: Ocular Immunology & Inflammation ranks 18 out of 59 in the Ophthalmology Category.Ocular Immunology and Inflammation is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and vision scientists. Published bimonthly, the journal provides an international medium for basic and clinical research reports on the ocular inflammatory response and its control by the immune system. The journal publishes original research papers, case reports, reviews, letters to the editor, meeting abstracts, and invited editorials.
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