Treatment of esophageal leakages with the Microtech®-VAC-Stent: a monocentric early experience of three cases.

IF 3 Q2 GASTROENTEROLOGY & HEPATOLOGY Therapeutic Advances in Gastrointestinal Endoscopy Pub Date : 2023-09-28 eCollection Date: 2023-01-01 DOI:10.1177/26317745231200312
Michelle A Klose, Jens Walldorf, Marko Damm, Sebastian Krug, Johannes Klose, Ulrich Ronellenfitsch, Joerg Kleeff, Patrick Michl, Jonas Rosendahl
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Abstract

Background: Endoscopic approaches in the treatment of transmural esophageal defects, either after esophageal resection or due to perforation, have demonstrated convincing feasibility. Surgical options are limited and associated with high morbidity and mortality rates. Currently, internal endoscopic drainage with pigtail stents, self-expanding metal stent (SEMS), or endoscopic vacuum therapy (EVT) are options for first-line treatment. Here, we report the outcome of the recently developed combination of SEMS and EVT using the endoscopic Microtech®-VAC-Stent (EVS).

Methods: Between June and July 2022, three consecutive patients (one female and two males) with esophageal transmural defects were treated with the Microtech®-VAC-Stent. Two patients suffered from an anastomotic leak after oncologic gastroesophageal surgery, and one patient presented with esophageal perforation due to Boerhaave syndrome.

Results: Three consecutive patients were successfully treated with EVS. In one patient, one EVS treatment was sufficient, whereas the other two patients needed two and six EVS exchanges. Exchanges were scheduled every 7 days and no procedural adverse events were observed.

Conclusion: In line with the former case series, EVS therapy is a promising new approach for the treatment of esophageal leaks. Exchange of the EVS seems feasible every 7 days reducing interventions for the individual patient. Prospective studies comparing EVS with other endoscopic therapies are needed to define the best therapeutic approach.

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Microtech®-VAC支架治疗食管瘘:三例单中心早期经验。
背景:内镜下治疗跨壁食管缺损的方法,无论是在食管切除术后还是由于穿孔,都已证明了令人信服的可行性。手术选择有限,且发病率和死亡率较高。目前,使用猪尾支架的内窥镜引流、自膨胀金属支架(SEMS)或内窥镜真空治疗(EVT)是一线治疗的选择。在此,我们报告了最近使用内镜Microtech®-VAC支架(EVS)开发的SEMS和EVT组合的结果。方法:2022年6月至7月,连续三名食管透壁缺损患者(一名女性和两名男性)使用Microtech®/VAC支架进行治疗。两名患者在肿瘤胃食管手术后发生吻合口瘘,一名患者因Boerhaave综合征出现食道穿孔。结果:连续3例患者成功接受EVS治疗。在一名患者中,一次EVS治疗就足够了,而其他两名患者需要两次和六次EVS交换。每7天安排一次交流 天,未观察到任何程序性不良事件。结论:与以往的病例系列一致,EVS治疗是一种很有前途的治疗食管瘘的新方法。电动车辆供电系统的更换似乎可行,每7次 减少个体患者干预的天数。需要对EVS与其他内窥镜疗法进行前瞻性研究,以确定最佳治疗方法。
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CiteScore
4.80
自引率
0.00%
发文量
8
审稿时长
13 weeks
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