Lymph node dissection effectively shortens the course of anti-tuberculosis treatment

Qibin Liu , Xiyong Dai , Xianxiang Chen , Xiaoyu Liu
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Abstract

Objective

To evaluate the clinical efficacy of postoperative ultra-short-course chemotherapy in treating cervical lymph node tuberculosis in the Wuhan region.

Methods

Follow-up of patients in the surgery and non-surgery group after discharge, evaluating the number of cervical lymph nodes during the administration of antituberculosis drugs.

Results

The age of the patients in the surgical therapy group ranged from 6 to 83 years old with an average age of 45 and a standard deviation of 20. The number of cervical lymph nodes in the patients ranged from 1.61 to 8.15. The average antituberculosis treatment duration before surgery for patients in the surgical group was 98.02 days, while for patients in the non-surgical group it was 96.13 days. The average length of hospital stay for patients receiving surgical treatment was 12.76 days, while for patients receiving non-surgical treatment it was 8.74 days. The average antituberculosis treatment duration after discharge for patients in the surgical group was 205 days, with a standard deviation of 42.39, while for patients in the non-surgical group it was 372 days, with a standard deviation of 71.54. The T-test results for antituberculosis treatment during hospitalization and after discharge were 98.3x10-10 and 5.02x10-67, respectively.

Conclusion

After surgical treatment of cervical lymph node tuberculosis, the effectiveness of a 4–6 month short-course chemotherapy in Wuhan region is not weaker than the effectiveness of a conventional 6–9 month drug treatment.

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淋巴结清扫有效缩短了抗结核治疗的疗程。
目的:评价武汉地区颈淋巴结结核术后超短期化疗的临床疗效。方法:对手术组和非手术组患者出院后进行随访,评估抗结核药物给药期间颈部淋巴结的数量。结果:手术治疗组患者年龄6~83岁,平均年龄45岁,标准差20岁。患者的颈部淋巴结数量在1.61到8.15之间。手术组患者术前平均抗结核治疗时间为98.02天,非手术组患者为96.13天。接受手术治疗的患者平均住院时间为12.76天,接受非手术治疗的患者为8.74天。手术组患者出院后平均抗结核治疗时间为205天,标准偏差为42.39,而非手术组患者为372天,标准差为71.54。住院期间和出院后抗结核治疗的T检验结果分别为98.3x10-10和5.02x10-67。结论:手术治疗颈淋巴结结核后,武汉地区4-6个月短程化疗的疗效并不弱于常规6-9个月药物治疗的疗效。
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来源期刊
Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
Journal of Clinical Tuberculosis and Other Mycobacterial Diseases Medicine-Pulmonary and Respiratory Medicine
CiteScore
4.00
自引率
5.00%
发文量
44
审稿时长
30 weeks
期刊介绍: Journal of Clinical Tuberculosis and Mycobacterial Diseases aims to provide a forum for clinically relevant articles on all aspects of tuberculosis and other mycobacterial infections, including (but not limited to) epidemiology, clinical investigation, transmission, diagnosis, treatment, drug-resistance and public policy, and encourages the submission of clinical studies, thematic reviews and case reports. Journal of Clinical Tuberculosis and Mycobacterial Diseases is an Open Access publication.
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