Katya Sacco, Lorna M Bonnici West, Lauren M Grech, Janet Krska, Maria Cordina
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引用次数: 0
Abstract
Objectives: Medication taking in the management of chronic conditions causes a significant burden on individuals. The aim of this study was to explore the medication-related burden in ambulatory adult patients with chronic conditions in Malta.
Methods: A cross-sectional survey utilising the living with medicines questionnaire V3 (LMQ V3) was conducted in Maltese residents over the age of 18 years, taking at least 1 medication for a chronic condition and recruited through community events. The overall LMQ score, the domain scores and the visual analog scale data were analysed to determine relationships with the demographic factors.
Results: A total of 337 responses were analysed revealing a moderate (42.4%) to high medication (36.8%) related burden. The drivers of medication-related burden were primarily: 'side-effects of prescribed medication' (r = -0.843, p < 0.001), 'attitudes/concerns about medicine use' (r = -0.830, p < 0.001) and 'impact/interferences to day-to-day life' (r = -0.820, p < 0.001). Lack of autonomy to vary the dosage regimen resulted in a higher burden (r = -0.260, p < 0.001). Males experienced an overall higher burden (p = 0.046) especially related to practical difficulties (p = 0.04), cost-related burden (p = 0.04) and side-effects of prescribed medication (p = 0.01).
Conclusion: Medication-related burden is complex and multi-faceted as demonstrated by the findings of this study. Healthcare professionals should seek to identify and address factors causing this burden to improve patient outcomes.
目的:慢性病治疗中的服药给个人带来了巨大的负担。本研究的目的是探讨马耳他门诊成年慢性病患者的药物相关负担。方法:使用药物生活问卷V3(LMQ V3)对18岁以上的马耳他居民进行横断面调查,他们至少服用了一种治疗慢性病的药物,并通过社区活动招募。分析总体LMQ评分、领域评分和视觉模拟量表数据,以确定与人口统计学因素的关系。结果:共分析了337例反应,显示中度(42.4%)至高度(36.8%)的药物相关负担。药物相关负担的驱动因素主要是:“处方药的副作用”(r = -0.843,p p p p p = 0.046),尤其与实际困难有关(p = 0.04),成本相关负担(p = 0.04)和处方药的副作用(p = 结论:本研究结果表明,药物相关负担是复杂而多方面的。医疗保健专业人员应设法识别和解决造成这种负担的因素,以改善患者的预后。
期刊介绍:
Chronic illnesses are prolonged, do not resolve spontaneously, and are rarely completely cured. The most common are cardiovascular diseases (hypertension, coronary artery disease, stroke and heart failure), the arthritides, asthma and chronic obstructive pulmonary disease, diabetes and epilepsy. There is increasing evidence that mental illnesses such as depression are best understood as chronic health problems. HIV/AIDS has become a chronic condition in those countries where effective medication is available.