Differentiated thyroid cancer - possible risks of treatment, suppressive therapy and adherence to current recommendations.

Q4 Medicine Vnitrni lekarstvi Pub Date : 2023-01-01 DOI:10.36290/vnl.2023.061
Petra Němčíková, Ludmila Brunerová
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Abstract

Thyroid carcinoma (TC) is rare and represents 1-2 % of all human tumors. The incidence of TC has been increasing worldwide. TC comprises of a heterogeneous group of tumours with variable biological activity. Women are mostly affected. TC can be divided in differentiated TC/DTCs (papillary - PTC, follicular - FTC, from Hürthle cells - HCC), medullary carcinoma - MTC and anaplastic thyroid cancer - ATC. In this article, we focus on possible pitfalls of suppression therapy (cardiovascular, bone and mental), particularly in low-risk patients, and we discuss the data on the adherence to guidelines for suppression therapy in DTC.

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分化型甲状腺癌症-可能的治疗风险、抑制性治疗和遵守当前建议。
甲状腺癌(TC)是罕见的,占所有人类肿瘤的1-2%。TC的发病率在全球范围内一直在增加。TC由一组具有可变生物活性的异质性肿瘤组成。妇女受到的影响最大。TC可分为分化型TC/DTC(乳头状-PTC、毛囊状-FTC,来自Hürthle细胞-HCC)、髓样癌-MTC和间变性甲状腺癌症-ATC。在这篇文章中,我们重点讨论了抑制治疗(心血管、骨骼和精神)的可能陷阱,特别是在低风险患者中,并讨论了DTC抑制治疗指南的遵守情况。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Vnitrni lekarstvi
Vnitrni lekarstvi Medicine-Internal Medicine
CiteScore
0.50
自引率
0.00%
发文量
104
期刊介绍: Vnitřní lékařství je tiskovým orgánem České internistické společnosti České lékařské společnosti Jana Evangelisty Purkyně a Slovenskej internistickej spoločnosti Slovenskej lekárskej spoločnosti. Je vydáván nepřetržitě od roku 1955. Časopis vychází jako měsíčník, tedy 12krát do roka a podle potřeby jsou v běžném ročníku vydávána jeho suplementa, která jsou obsahově zaměřena k určitému tématu. Tematicky je časopis zaměřen široce na oblast interní medicíny se zvláštní pozorností ke kardiologii, diabetologii a poruchám metabolizmu.
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