Practice patterns and considerations in liver transplantation from living donors with high BMI: A review.

IF 1.2 Q4 GASTROENTEROLOGY & HEPATOLOGY Hepatology Forum Pub Date : 2023-09-20 eCollection Date: 2023-01-01 DOI:10.14744/hf.2023.2023.0030

Carl Samaha, Hadi Chaaban, Cem Simsek, Nilay Danis, Jessica S Lin, Ahmet Gurakar

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Abstract

Living Donor Liver Transplantation (LDLT) is a valuable solution to the shortage of donor organs for patients with end-stage liver disease. However, the eligibility of obese donors for LDLT remains a subject of debate. This literature review explores global practices and perceptions of LDLT, identifies donor eligibility criteria, and discusses special considerations and ethical caveats. The review highlights the need for standardized guidelines for donor selection, considering the global distribution of Body mass index and variations in population-specific criteria. It also emphasizes the importance of non-invasive testing and pre-operative optimization of liver steatosis for select obese donors. Furthermore, the review examines the outcomes and complications associated with obese donors in LDLT. The findings of this review contribute to the ongoing discussion on the inclusion of obese donors in LDLT and provide insights for future research and guideline development.

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高BMI活体供体肝移植的实践模式和注意事项：综述。

活体肝移植（LDLT）是解决终末期肝病患者供体器官短缺的一种有价值的方法。然而，肥胖捐赠者是否有资格接受LDLT仍然是一个争论的话题。这篇文献综述探讨了LDLT的全球实践和看法，确定了捐赠者资格标准，并讨论了特殊考虑因素和道德注意事项。审查强调，考虑到体重指数的全球分布和特定人群标准的差异，有必要制定捐赠者选择的标准化指南。它还强调了非侵入性检测和术前优化肝脂肪变性对选择肥胖捐赠者的重要性。此外，该综述检查了LDLT中与肥胖供体相关的结果和并发症。这篇综述的发现有助于正在进行的关于将肥胖捐赠者纳入LDLT的讨论，并为未来的研究和指南制定提供见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Hepatology Forum

CiteScore

1.90

自引率

12.50%

发文量