Improved glycemic control after the use of flash glucose monitoring accompanied by improved treatment satisfaction in patients with non-insulin-treated type 2 diabetes: A post-hoc analysis of a randomized controlled trial

IF 2.6 4区医学 Q3 ENDOCRINOLOGY & METABOLISM Primary Care Diabetes Pub Date : 2023-12-01 DOI:10.1016/j.pcd.2023.09.009

Ayaka Hayase , Takeshi Onoue , Tomoko Kobayashi , Eri Wada , Tomoko Handa , Tamaki Kinoshita , Ayana Yamagami , Yoshinori Yasuda , Shintaro Iwama , Yohei Kawaguchi , Takashi Miyata , Mariko Sugiyama , Hiroshi Takagi , Daisuke Hagiwara , Hidetaka Suga , Ryoichi Banno , Yachiyo Kuwatsuka , Masahiko Ando , Motomitsu Goto , Hiroshi Arima

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Abstract

Aims

In our previously reported randomized controlled trial in patients with noninsulin-treated type 2 diabetes, the use of flash glucose monitoring (FGM) improved glycated hemoglobin (HbA1c), and the improvement was sustained after the cessation of glucose monitoring. In this post-hoc analysis, we examined data from our trial to identify the factors that influenced FGM efficacy.

Methods

We analyzed data for 48 of 49 participants of the FGM group who completed the trial to clarify the changes in various parameters and factors related to HbA1c improvement with the use of FGM.

Results

Analyses of the FGM data during the 12-week FGM provision period showed that the weekly mean blood glucose levels considerably decreased as early as at 1 week compared with the baseline values, and this decline continued for 12 weeks. An enhancement in the Diabetes Treatment Satisfaction Questionnaire regarding “willingness to continue the current treatment” score was significantly associated with the improvement in HbA1c at 12 (p = 0.009) and 24 weeks (p = 0.012).

Conclusions

Glycemic control was improved soon after FGM initiation, accompanied by improved satisfaction with continuation of the current treatment in patients with noninsulin-treated type 2 diabetes.

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非胰岛素治疗的2型糖尿病患者使用快速血糖监测后血糖控制改善，同时治疗满意度提高：一项随机对照试验的事后分析。

目的：在我们之前报道的非胰岛素治疗的2型糖尿病患者的随机对照试验中，使用快速血糖监测（FGM）改善了糖化血红蛋白（HbA1c），并且在停止血糖监测后这种改善是持续的。在这项事后分析中，我们检查了试验数据，以确定影响女性生殖器切割疗效的因素。方法：我们分析了49名完成试验的女性生殖器切割组参与者中的48人的数据，以阐明使用女性生殖器切割后与HbA1c改善相关的各种参数和因素的变化这种下降持续了12周。糖尿病治疗满意度问卷中关于“是否愿意继续目前的治疗”评分的提高与12周（p=0.009）和24周（p=0.012）时HbA1c的改善显著相关，伴随着非胰岛素治疗的2型糖尿病患者对继续目前治疗的满意度提高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Primary Care Diabetes ENDOCRINOLOGY & METABOLISM-PRIMARY HEALTH CARE

CiteScore

5.00

自引率

3.40%

发文量

134

审稿时长

47 days

期刊介绍： The journal publishes original research articles and high quality reviews in the fields of clinical care, diabetes education, nutrition, health services, psychosocial research and epidemiology and other areas as far as is relevant for diabetology in a primary-care setting. The purpose of the journal is to encourage interdisciplinary research and discussion between all those who are involved in primary diabetes care on an international level. The Journal also publishes news and articles concerning the policies and activities of Primary Care Diabetes Europe and reflects the society''s aim of improving the care for people with diabetes mellitus within the primary-care setting.