Primary Care Diabetes最新文献

英文中文

Sociodemographic and behavioral factors associated with diet quality in low-income adults with prediabetes and type 2 diabetes 与糖尿病前期和2型糖尿病低收入成人饮食质量相关的社会人口统计学和行为因素

IF 2.3 4区医学 Q3 ENDOCRINOLOGY & METABOLISM

Primary Care Diabetes

Pub Date : 2026-02-01 Epub Date: 2025-11-26 DOI: 10.1016/j.pcd.2025.11.008

Kristine D. Gu , Daniel Shinnick , Tanayott Thaweethai , Jessica Cheng , Deborah J. Wexler , Anne N. Thorndike

Aims

Low-income adults face barriers to diabetes prevention and self-management, especially healthy eating. This study assessed factors associated with diet quality in low-income adults with prediabetes or type 2 diabetes (T2D), particularly modifiable factors that could be targeted in diabetes self-management education and support (DSMES).

Methods

This secondary analysis of a cohort of low-income health center patients in Boston, Massachusetts determined the association between diet quality and sociodemographic (e.g., race/ethnicity, social support) and behavioral (e.g., depression) factors in adults with prediabetes or T2D. Primary outcome was Healthy Eating Index-2020 (HEI; range 0–100, higher=healthier). Random forests, interpreted using Shapley Additive Explanation values, were fit to determine relative importance of factors in predicting HEI.

Results

Of 278 participants, 42 % had prediabetes and 58 % had T2D. Median age (IQR) was 52 (43, 57); 58 % were Hispanic. Top factors associated with higher HEI were older age, female gender, and Hispanic ethnicity; other important factors were non-smoking, greater dietary variety, less time sitting, higher sleep quality, lower stress, more social support, and fewer depression symptoms.

Conclusion

Modifiable factors for low diet quality, such as dietary variety, social support, and stress, could be emphasized in diabetes prevention and DSMES programs tailored for low-income populations.

目的：低收入成年人在糖尿病预防和自我管理方面面临障碍，尤其是健康饮食。本研究评估了与糖尿病前期或2型糖尿病（T2D）的低收入成年人饮食质量相关的因素，特别是糖尿病自我管理教育和支持（DSMES）中可改变的因素。方法：对马萨诸塞州波士顿低收入健康中心的一组患者进行二次分析，确定了糖尿病前期或t2dm患者饮食质量与社会人口学（如种族/民族、社会支持）和行为（如抑郁）因素之间的关系。主要终点是健康饮食指数-2020 （HEI；范围0-100，越高越健康）。随机森林，解释使用沙普利加性解释值，拟合，以确定相对重要性的因素，在预测HEI。结果：278名参与者中，42% %患有前驱糖尿病，58% %患有T2D。中位年龄（IQR）为52 (43,57)；58% %是西班牙裔。与高HEI相关的主要因素是年龄较大、女性性别和西班牙裔；其他重要因素包括不吸烟、饮食更多样化、坐着的时间更少、睡眠质量更高、压力更小、社会支持更多、抑郁症状更少。结论：在针对低收入人群的糖尿病预防和DSMES项目中，饮食多样性、社会支持和压力等饮食质量低的可改变因素应得到重视。

{"title":"Sociodemographic and behavioral factors associated with diet quality in low-income adults with prediabetes and type 2 diabetes","authors":"Kristine D. Gu , Daniel Shinnick , Tanayott Thaweethai , Jessica Cheng , Deborah J. Wexler , Anne N. Thorndike","doi":"10.1016/j.pcd.2025.11.008","DOIUrl":"10.1016/j.pcd.2025.11.008","url":null,"abstract":"<div><h3>Aims</h3><div>Low-income adults face barriers to diabetes prevention and self-management, especially healthy eating. This study assessed factors associated with diet quality in low-income adults with prediabetes or type 2 diabetes (T2D), particularly modifiable factors that could be targeted in diabetes self-management education and support (DSMES).</div></div><div><h3>Methods</h3><div>This secondary analysis of a cohort of low-income health center patients in Boston, Massachusetts determined the association between diet quality and sociodemographic (e.g., race/ethnicity, social support) and behavioral (e.g., depression) factors in adults with prediabetes or T2D. Primary outcome was Healthy Eating Index-2020 (HEI; range 0–100, higher=healthier). Random forests, interpreted using Shapley Additive Explanation values, were fit to determine relative importance of factors in predicting HEI.</div></div><div><h3>Results</h3><div>Of 278 participants, 42 % had prediabetes and 58 % had T2D. Median age (IQR) was 52 (43, 57); 58 % were Hispanic. Top factors associated with higher HEI were older age, female gender, and Hispanic ethnicity; other important factors were non-smoking, greater dietary variety, less time sitting, higher sleep quality, lower stress, more social support, and fewer depression symptoms.</div></div><div><h3>Conclusion</h3><div>Modifiable factors for low diet quality, such as dietary variety, social support, and stress, could be emphasized in diabetes prevention and DSMES programs tailored for low-income populations.</div></div>","PeriodicalId":48997,"journal":{"name":"Primary Care Diabetes","volume":"20 1","pages":"Pages 120-126"},"PeriodicalIF":2.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145644188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative risk of osteoporosis in older women with type 2 diabetes receiving sodium–glucose cotransporter 2 inhibitor or dipeptidyl peptidase-4 inhibitor: A nationwide cohort study 接受钠-葡萄糖共转运蛋白2抑制剂或二肽基肽酶-4抑制剂治疗的老年2型糖尿病女性骨质疏松的比较风险：一项全国性队列研究

IF 2.3 4区医学 Q3 ENDOCRINOLOGY & METABOLISM

Primary Care Diabetes

Pub Date : 2026-02-01 Epub Date: 2025-12-23 DOI: 10.1016/j.pcd.2025.12.005

Hyeon Jeong Lee, Pusoon Chun

Aim

To compare osteoporosis risk associated with sodium–glucose cotransporter 2 inhibitor (SGLT2i) versus dipeptidyl peptidase-4 inhibitor (DPP-4i) in older women with type 2 diabetes (T2D).

Methods

This cohort study used the Korean National Health Insurance database. Adjusted hazard ratios (aHRs) were estimated using multivariable Cox regression. Sensitivity analysis was performed using inverse probability of treatment weighting (IPTW).

Results

Among 1715,337 women aged ≥ 55 years with T2D, 5364 SGLT2i users and 26,504 DPP-4i users were analyzed. The incidence rates of osteoporosis were 6.7 (95 % CI, 6.0–7.4) and 7.0 (95 % CI, 6.7–7.3) per 100 person-years in the SGLT2i and DPP-4i groups, respectively. Osteoporosis risk with SGLT2i was comparable to DPP-4i (aHR, 0.93; 95 % CI, 0.89–1.04). These results remained consistent in the sensitivity analysis using IPTW (aHR, 0.95; 95 % CI, 0.89–1.00). Subgroup analyses showed a slightly lower osteoporosis risk with SGLT2i in patients aged 55–64 years (aHR, 0.84; 95 % CI, 0.76–0.93), those without prior rheumatoid arthritis (aHR, 0.90; 95 % CI, 0.83–0.97), proton pump inhibitor use (aHR, 0.88; 95 % CI, 0.80–0.96), or oral corticosteroid use (aHRs, 0.91; 95 % CI, 0.85–0.97).

Conclusion

SGLT2i was comparable to DPP-4i in osteoporosis risk among older women with T2D.

目的：比较老年2型糖尿病（T2D）女性中钠-葡萄糖共转运蛋白2抑制剂（sglti）与二肽基肽酶4抑制剂（DPP-4i）的骨质疏松风险。方法：本队列研究使用韩国国民健康保险数据库。校正风险比（aHRs）采用多变量Cox回归估计。采用处理加权逆概率（IPTW）进行敏感性分析。结果：在1715名年龄≥ 55岁的T2D女性中，分析了5364名SGLT2i使用者和26,504名DPP-4i使用者。在SGLT2i组和DPP-4i组中，骨质疏松症的发病率分别为每100人年6.7（95 % CI, 6.0-7.4）和7.0（95 % CI, 6.7-7.3）。SGLT2i的骨质疏松风险与DPP-4i相当（aHR, 0.93; 95 % CI, 0.89-1.04）。这些结果在IPTW敏感性分析中保持一致（aHR, 0.95; 95 % CI, 0.89-1.00）。亚组分析显示，55-64岁（aHR, 0.84; 95 % CI, 0.76-0.93）、既往无类风湿关节炎（aHR, 0.90; 95 % CI, 0.83-0.97）、使用质子泵抑制剂（aHR, 0.88; 95 % CI, 0.80-0.96）或口服皮质类固醇（aHR, 0.91; 95 % CI, 0.85-0.97）的SGLT2i患者骨质疏松风险略低。结论：SGLT2i与DPP-4i在老年T2D女性骨质疏松风险方面具有可比性。

{"title":"Comparative risk of osteoporosis in older women with type 2 diabetes receiving sodium–glucose cotransporter 2 inhibitor or dipeptidyl peptidase-4 inhibitor: A nationwide cohort study","authors":"Hyeon Jeong Lee, Pusoon Chun","doi":"10.1016/j.pcd.2025.12.005","DOIUrl":"10.1016/j.pcd.2025.12.005","url":null,"abstract":"<div><h3>Aim</h3><div>To compare osteoporosis risk associated with sodium–glucose cotransporter 2 inhibitor (SGLT2i) versus dipeptidyl peptidase-4 inhibitor (DPP-4i) in older women with type 2 diabetes (T2D).</div></div><div><h3>Methods</h3><div>This cohort study used the Korean National Health Insurance database. Adjusted hazard ratios (aHRs) were estimated using multivariable Cox regression. Sensitivity analysis was performed using inverse probability of treatment weighting (IPTW).</div></div><div><h3>Results</h3><div>Among 1715,337 women aged ≥ 55 years with T2D, 5364 SGLT2i users and 26,504 DPP-4i users were analyzed. The incidence rates of osteoporosis were 6.7 (95 % CI, 6.0–7.4) and 7.0 (95 % CI, 6.7–7.3) per 100 person-years in the SGLT2i and DPP-4i groups, respectively. Osteoporosis risk with SGLT2i was comparable to DPP-4i (aHR, 0.93; 95 % CI, 0.89–1.04). These results remained consistent in the sensitivity analysis using IPTW (aHR, 0.95; 95 % CI, 0.89–1.00). Subgroup analyses showed a slightly lower osteoporosis risk with SGLT2i in patients aged 55–64 years (aHR, 0.84; 95 % CI, 0.76–0.93), those without prior rheumatoid arthritis (aHR, 0.90; 95 % CI, 0.83–0.97), proton pump inhibitor use (aHR, 0.88; 95 % CI, 0.80–0.96), or oral corticosteroid use (aHRs, 0.91; 95 % CI, 0.85–0.97).</div></div><div><h3>Conclusion</h3><div>SGLT2i was comparable to DPP-4i in osteoporosis risk among older women with T2D.</div></div>","PeriodicalId":48997,"journal":{"name":"Primary Care Diabetes","volume":"20 1","pages":"Pages 106-114"},"PeriodicalIF":2.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145829564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on ‘Non-insulin-based markers of insulin resistance at diabetes diagnosis: A pooled analysis of 14 national health surveys’ 对《糖尿病诊断中胰岛素抵抗的非胰岛素基础标志物：对14个国家健康调查的汇总分析》的评论

IF 2.3 4区医学 Q3 ENDOCRINOLOGY & METABOLISM

Primary Care Diabetes

Pub Date : 2026-02-01 Epub Date: 2025-12-05 DOI: 10.1016/j.pcd.2025.11.010

Long Pu

This commentary provides methodological reflections on a recent multi-country study investigating insulin resistance (IR) marker heterogeneity in adults newly diagnosed with diabetes across 14 low and middle-income countries (LMICs). While commending the significant contribution of this research, we highlight three key considerations to refine the interpretation of findings and guide future studies. First, we discuss the need for population-specific validation of non-insulin-based IR markers, as their performance varies substantially across ethnic groups. Second, we examine the implications of relying on a single fasting glucose measurement for diabetes diagnosis, which may impact phenotypic characterization and subtype differentiation. Finally, we explore the importance of quantifying the relative contributions of multi-level factors—including adiposity, lifestyle, and healthcare system variables—to better understand the observed cross-country heterogeneity. Addressing these methodological aspects in future research will strengthen the evidence base for developing tailored diabetes care strategies in diverse global populations.

本评论提供了对最近一项多国研究的方法学反思，该研究在14个低收入和中等收入国家（LMICs）中调查了新诊断为糖尿病的成人胰岛素抵抗（IR）标志物的异质性。在赞扬这项研究的重大贡献的同时，我们强调了三个关键的考虑因素，以完善对研究结果的解释并指导未来的研究。首先，我们讨论了非基于胰岛素的IR标记物在人群特异性验证的必要性，因为它们的表现在不同的种族群体中差异很大。其次，我们研究了依赖单一空腹血糖测量对糖尿病诊断的影响，这可能会影响表型表征和亚型分化。最后，我们探讨了量化多层次因素（包括肥胖、生活方式和医疗系统变量）的相对贡献的重要性，以便更好地理解所观察到的跨国异质性。在未来的研究中解决这些方法学方面的问题，将加强在全球不同人群中制定量身定制的糖尿病护理策略的证据基础。

{"title":"Comment on ‘Non-insulin-based markers of insulin resistance at diabetes diagnosis: A pooled analysis of 14 national health surveys’","authors":"Long Pu","doi":"10.1016/j.pcd.2025.11.010","DOIUrl":"10.1016/j.pcd.2025.11.010","url":null,"abstract":"<div><div>This commentary provides methodological reflections on a recent multi-country study investigating insulin resistance (IR) marker heterogeneity in adults newly diagnosed with diabetes across 14 low and middle-income countries (LMICs). While commending the significant contribution of this research, we highlight three key considerations to refine the interpretation of findings and guide future studies. First, we discuss the need for population-specific validation of non-insulin-based IR markers, as their performance varies substantially across ethnic groups. Second, we examine the implications of relying on a single fasting glucose measurement for diabetes diagnosis, which may impact phenotypic characterization and subtype differentiation. Finally, we explore the importance of quantifying the relative contributions of multi-level factors—including adiposity, lifestyle, and healthcare system variables—to better understand the observed cross-country heterogeneity. Addressing these methodological aspects in future research will strengthen the evidence base for developing tailored diabetes care strategies in diverse global populations.</div></div>","PeriodicalId":48997,"journal":{"name":"Primary Care Diabetes","volume":"20 1","pages":"Page 145"},"PeriodicalIF":2.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145688779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mental health, substance abuse, and diabetes in low-income populations: A call for targeted research 低收入人群的心理健康、药物滥用和糖尿病：呼吁进行针对性研究。

IF 2.3 4区医学 Q3 ENDOCRINOLOGY & METABOLISM

Primary Care Diabetes

Pub Date : 2026-02-01 Epub Date: 2025-11-06 DOI: 10.1016/j.pcd.2025.10.009

Syeda Shajia Shahid Gillani, Zainab Binte Tahir, Mahrosh Iftikhar, Zenia Safwan

引用次数: 0

Editorial Board and Aims & Scopes 编辑委员会和目标与范围

IF 2.3 4区医学 Q3 ENDOCRINOLOGY & METABOLISM

Primary Care Diabetes

Pub Date : 2026-02-01 Epub Date: 2026-02-02 DOI: 10.1016/S1751-9918(26)00010-0

引用次数: 0

Glycemic status and effect on mortality: Multifactorial prevention programme for cardiovascular disease in Finnish primary care 血糖状态及其对死亡率的影响：芬兰初级保健心血管疾病的多因素预防方案。

IF 2.3 4区医学 Q3 ENDOCRINOLOGY & METABOLISM

Primary Care Diabetes

Pub Date : 2026-02-01 Epub Date: 2025-11-07 DOI: 10.1016/j.pcd.2025.11.001

Zhipeng Dou, Lele Peng

引用次数: 0

Impact of real-time continuous glucose monitoring and personalized digital health coaching on glycemic control and lifestyle in patients with type 2 diabetes and prediabetes 实时连续血糖监测和个性化数字健康指导对2型糖尿病及前驱糖尿病患者血糖控制和生活方式的影响

IF 2.3 4区医学 Q3 ENDOCRINOLOGY & METABOLISM

Primary Care Diabetes

Pub Date : 2026-02-01 Epub Date: 2025-12-13 DOI: 10.1016/j.pcd.2025.12.002

Yujin Park , Hye Rin Choi , Ji-eun Lee , Boram Choi , Chang-bo Noh , Jae-Heon Kang , Ye Seul Bae

Objective

This study evaluated the impact of real-time continuous glucose monitoring (CGM) combined with personalized digital health coaching on glycemic control and lifestyle behaviors in individuals with type 2 diabetes (T2DM) and prediabetes.

Method

A prospective cohort study was conducted involving 110 participants recruited from a chronic disease management service. The participants underwent an 8-week intervention where CGM data were used to provide real-time feedback, complemented by personalized lifestyle coaching. Baseline and post-intervention data included fasting blood glucose (FBG), glycated hemoglobin (HbA1c), body mass index (BMI), and lifestyle factors such as physical activity and eating habits. Participants were divided into tertiles based on mean amplitude of glycemic excursion (MAGE) to evaluate the effects of the intervention by glycemic variability (GV) level.

Results

Significant improvements in glycemic control were observed across all tertiles. The highest GV group (T3) showed the greatest reductions in HbA1c (7.39 % to 6.82 %, p = 0.004) and FBG. The physical activity scores significantly increased in the T3 group (p = 0.005), and all tertiles reported healthier dietary habits following the intervention.

Conclusions

The integration of CGM with personalized digital health coaching was associated with significant short-term improvements in glycemic control and lifestyle behaviors, particularly among individuals with high GV.

目的：本研究评估实时连续血糖监测（CGM）结合个性化数字健康指导对2型糖尿病（T2DM）及前驱糖尿病患者血糖控制和生活方式行为的影响。方法：一项前瞻性队列研究，涉及110名来自慢性疾病管理服务的参与者。参与者接受了为期8周的干预，其中CGM数据用于提供实时反馈，并辅以个性化的生活方式指导。基线和干预后数据包括空腹血糖（FBG）、糖化血红蛋白（HbA1c）、体重指数（BMI）和生活方式因素，如体力活动和饮食习惯。根据血糖偏移的平均幅度（MAGE）将参与者分为四位数，以评估血糖变异性（GV）水平干预的效果。结果：所有受试者的血糖控制均有显著改善。GV最高组（T3）的HbA1c（7.39 %至6.82 %,p = 0.004）和FBG的降低幅度最大。T3组的身体活动得分显著提高（p = 0.005），所有受试者在干预后都报告了更健康的饮食习惯。结论：CGM与个性化数字健康指导的整合与血糖控制和生活方式行为的显着短期改善有关，特别是在GV高的个体中。

{"title":"Impact of real-time continuous glucose monitoring and personalized digital health coaching on glycemic control and lifestyle in patients with type 2 diabetes and prediabetes","authors":"Yujin Park , Hye Rin Choi , Ji-eun Lee , Boram Choi , Chang-bo Noh , Jae-Heon Kang , Ye Seul Bae","doi":"10.1016/j.pcd.2025.12.002","DOIUrl":"10.1016/j.pcd.2025.12.002","url":null,"abstract":"<div><h3>Objective</h3><div>This study evaluated the impact of real-time continuous glucose monitoring (CGM) combined with personalized digital health coaching on glycemic control and lifestyle behaviors in individuals with type 2 diabetes (T2DM) and prediabetes.</div></div><div><h3>Method</h3><div>A prospective cohort study was conducted involving 110 participants recruited from a chronic disease management service. The participants underwent an 8-week intervention where CGM data were used to provide real-time feedback, complemented by personalized lifestyle coaching. Baseline and post-intervention data included fasting blood glucose (FBG), glycated hemoglobin (HbA1c), body mass index (BMI), and lifestyle factors such as physical activity and eating habits. Participants were divided into tertiles based on mean amplitude of glycemic excursion (MAGE) to evaluate the effects of the intervention by glycemic variability (GV) level.</div></div><div><h3>Results</h3><div>Significant improvements in glycemic control were observed across all tertiles. The highest GV group (T3) showed the greatest reductions in HbA1c (7.39 % to 6.82 %, p = 0.004) and FBG. The physical activity scores significantly increased in the T3 group (p = 0.005), and all tertiles reported healthier dietary habits following the intervention.</div></div><div><h3>Conclusions</h3><div>The integration of CGM with personalized digital health coaching was associated with significant short-term improvements in glycemic control and lifestyle behaviors, particularly among individuals with high GV.</div></div>","PeriodicalId":48997,"journal":{"name":"Primary Care Diabetes","volume":"20 1","pages":"Pages 61-67"},"PeriodicalIF":2.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145752347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of frailty on foot care behaviors and self-efficacy in middle-aged and older adults with type 2 diabetes 虚弱对中老年2型糖尿病患者足部护理行为和自我效能的影响

IF 2.3 4区医学 Q3 ENDOCRINOLOGY & METABOLISM

Primary Care Diabetes

Pub Date : 2026-02-01 Epub Date: 2025-11-21 DOI: 10.1016/j.pcd.2025.11.009

Döndü Bilici , Meryem Kılıç

Background

Frailty is increasingly recognized as a condition that negatively affects self-management in individuals with type 2 diabetes. Limited evidence exists regarding its impact on diabetic foot self-care and self-efficacy, particularly in middle-aged populations.

Objectives

This study aimed to examine the effect of frailty on foot care behaviors and self-efficacy among middle-aged and older adults with type 2 diabetes.

Methods

A descriptive, cross-sectional study was conducted with 75 middle-aged (40–64 years) and 75 older (≥65 years) adults diagnosed with type 2 diabetes. Data were collected using the FRAIL Scale, the Foot Care Behavior Scale, and the Diabetic Foot Care Self-Efficacy Scale. Group comparisons were performed using independent t-tests, and regression analyses were used to evaluate the predictive role of frailty.

Results

Frailty prevalence was 22.7 % in middle-aged adults and 42.7 % in older adults. Regression analyses showed that frailty was a strong predictor of both self-efficacy and foot care behaviors. Each one-point increase in frailty score was associated with a ∼12-point decrease in self-efficacy (β=-0.876; p < 0.001) and an ∼8-point decrease in foot care behaviors (β=-0.905; p < 0.001). The explanatory power of frailty was greater in middle-aged adults compared to older adults.

Conclusion

Frailty significantly impairs foot care behaviors and self-efficacy in adults with type 2 diabetes. Routine frailty screening, even from middle age, may support the early identification of individuals at risk for diabetic foot complications and inform preventive wound care strategies.

背景：虚弱越来越被认为是对2型糖尿病患者自我管理产生负面影响的一种状况。关于它对糖尿病足自我保健和自我效能的影响，特别是在中年人群中，证据有限。目的：本研究旨在探讨虚弱对中老年2型糖尿病患者足部护理行为和自我效能感的影响。方法：对75名诊断为2型糖尿病的中年人（40-64岁）和75名老年人（≥65岁）进行描述性横断面研究。采用体弱量表、足部护理行为量表和糖尿病足部护理自我效能量表收集数据。采用独立t检验进行组间比较，并采用回归分析评估虚弱的预测作用。结果：中老年人和老年人的衰弱患病率分别为22.7% %和42.7% %。回归分析显示，虚弱是自我效能感和足部护理行为的强预测因子。虚弱评分每增加1分，自我效能感就会降低~ 12分（β=-0.876; p ）。结论：虚弱显著影响2型糖尿病成人足部护理行为和自我效能感。常规虚弱筛查，甚至从中年开始，可以支持早期识别有糖尿病足并发症风险的个体，并告知预防性伤口护理策略。

{"title":"Impact of frailty on foot care behaviors and self-efficacy in middle-aged and older adults with type 2 diabetes","authors":"Döndü Bilici , Meryem Kılıç","doi":"10.1016/j.pcd.2025.11.009","DOIUrl":"10.1016/j.pcd.2025.11.009","url":null,"abstract":"<div><h3>Background</h3><div>Frailty is increasingly recognized as a condition that negatively affects self-management in individuals with type 2 diabetes. Limited evidence exists regarding its impact on diabetic foot self-care and self-efficacy, particularly in middle-aged populations.</div></div><div><h3>Objectives</h3><div>This study aimed to examine the effect of frailty on foot care behaviors and self-efficacy among middle-aged and older adults with type 2 diabetes.</div></div><div><h3>Methods</h3><div>A descriptive, cross-sectional study was conducted with 75 middle-aged (40–64 years) and 75 older (≥65 years) adults diagnosed with type 2 diabetes. Data were collected using the FRAIL Scale, the Foot Care Behavior Scale, and the Diabetic Foot Care Self-Efficacy Scale. Group comparisons were performed using independent t-tests, and regression analyses were used to evaluate the predictive role of frailty.</div></div><div><h3>Results</h3><div>Frailty prevalence was 22.7 % in middle-aged adults and 42.7 % in older adults. Regression analyses showed that frailty was a strong predictor of both self-efficacy and foot care behaviors. Each one-point increase in frailty score was associated with a ∼12-point decrease in self-efficacy (β=-0.876; p < 0.001) and an ∼8-point decrease in foot care behaviors (β=-0.905; p < 0.001). The explanatory power of frailty was greater in middle-aged adults compared to older adults.</div></div><div><h3>Conclusion</h3><div>Frailty significantly impairs foot care behaviors and self-efficacy in adults with type 2 diabetes. Routine frailty screening, even from middle age, may support the early identification of individuals at risk for diabetic foot complications and inform preventive wound care strategies.</div></div>","PeriodicalId":48997,"journal":{"name":"Primary Care Diabetes","volume":"20 1","pages":"Pages 115-119"},"PeriodicalIF":2.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145582496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Type 2 diabetes monitoring and control in migrants and non-migrants: A population-based cohort study in primary care in the Netherlands 移民和非移民的2型糖尿病监测和控制：荷兰一项基于人群的初级保健队列研究

IF 2.3 4区医学 Q3 ENDOCRINOLOGY & METABOLISM

Primary Care Diabetes

Pub Date : 2026-02-01 Epub Date: 2025-10-15 DOI: 10.1016/j.pcd.2025.10.003

B.T. Strooij , S. Remmelzwaal , M. Muilwijk , J.A. Overbeek , R.M.C. Herings , P.J.M. Elders , H.P.J. van Hout , O.R. Maarsingh , I.G.M. van Valkengoed , M.T. Blom

Aims

Type 2 diabetes (T2D) disproportionally affects migrants. We compared T2D-care in primary care between migrants and non-migrants in the Netherlands.

Methods

We performed a dynamic cohort study based on routine care data (2015–2019) from the DIAbetes MANagement and Treatment (DIAMANT) cohort linked to databases of Statistics Netherlands. Persons aged ≥ 35years with T2D treated in primary care were included. Outcomes included annual monitoring of HbA1c, systolic blood pressure and LDL; meeting of treatment targets; and medication prescription. Generalized estimating equations logistic regression models estimated the associations between having a migration background and outcomes.

Results

We included 165,670 persons: 83.7 % non-migrants, 2.1 % Turkish, 3.0 % Moroccan, 2.1 % Surinamese, 3.3 % European, and 5.7 % other non-European migrants. Most migrant groups had similar or higher odds of having annual monitoring compared to non-migrants, but lower odds of meeting the HbA1c and LDL treatment targets, with the lowest odds for Turkish migrants (OR 0.61, 95 %-CI 0.57–0.64; OR 0.86, 95 %-CI 0.81–0.91). Exploratory analyses demonstrated insulins to be less often prescribed to migrants.

Conclusions

Most migrant groups were equally or better monitored for T2D-parameters compared to non-migrants, but were less likely to meet HbA1c targets. This might partly reflect the less frequent insulin prescriptions to migrants. Further research is needed on underlying mechanisms and the specific needs of migrant groups to optimize T2D-care for all.

目的：2型糖尿病（T2D）对移民的影响不成比例。我们比较了荷兰移民和非移民在初级保健中的t2d护理。方法：我们基于与荷兰统计局数据库相关联的糖尿病管理和治疗（DIAMANT）队列的常规护理数据（2015-2019）进行了一项动态队列研究。年龄≥ ，35岁，接受初级保健治疗的T2D患者。结果包括每年监测HbA1c、收缩压和LDL；达到治疗目标；还有药物处方。广义估计方程逻辑回归模型估计具有迁移背景和结果之间的关联。结果：我们纳入了165,670人：83.7 %非移民，2.1 %土耳其人，3.0 %摩洛哥人，2.1 %苏里南人，3.3 %欧洲人和5.7 %其他非欧洲移民。与非移民相比，大多数移民群体每年进行监测的几率相似或更高，但达到HbA1c和LDL治疗目标的几率较低，土耳其移民的几率最低（or 0.61, 95 %-CI 0.57-0.64; or 0.86, 95 %-CI 0.81-0.91）。探索性分析表明，移民较少使用胰岛素。结论：与非移民相比，大多数移民群体的t2d参数监测相同或更好，但达到HbA1c目标的可能性较小。这可能在一定程度上反映了给移民开胰岛素的频率较低。需要进一步研究移民群体的潜在机制和具体需求，以优化所有人的t2d护理。

{"title":"Type 2 diabetes monitoring and control in migrants and non-migrants: A population-based cohort study in primary care in the Netherlands","authors":"B.T. Strooij , S. Remmelzwaal , M. Muilwijk , J.A. Overbeek , R.M.C. Herings , P.J.M. Elders , H.P.J. van Hout , O.R. Maarsingh , I.G.M. van Valkengoed , M.T. Blom","doi":"10.1016/j.pcd.2025.10.003","DOIUrl":"10.1016/j.pcd.2025.10.003","url":null,"abstract":"<div><h3>Aims</h3><div>Type 2 diabetes (T2D) disproportionally affects migrants. We compared T2D-care in primary care between migrants and non-migrants in the Netherlands.</div></div><div><h3>Methods</h3><div>We performed a dynamic cohort study based on routine care data (2015–2019) from the DIAbetes MANagement and Treatment (DIAMANT) cohort linked to databases of Statistics Netherlands. Persons aged ≥ 35years with T2D treated in primary care were included. Outcomes included annual monitoring of HbA1c, systolic blood pressure and LDL; meeting of treatment targets; and medication prescription. Generalized estimating equations logistic regression models estimated the associations between having a migration background and outcomes.</div></div><div><h3>Results</h3><div>We included 165,670 persons: 83.7 % non-migrants, 2.1 % Turkish, 3.0 % Moroccan, 2.1 % Surinamese, 3.3 % European, and 5.7 % other non-European migrants. Most migrant groups had similar or higher odds of having annual monitoring compared to non-migrants, but lower odds of meeting the HbA1c and LDL treatment targets, with the lowest odds for Turkish migrants (OR 0.61, 95 %-CI 0.57–0.64; OR 0.86, 95 %-CI 0.81–0.91). Exploratory analyses demonstrated insulins to be less often prescribed to migrants.</div></div><div><h3>Conclusions</h3><div>Most migrant groups were equally or better monitored for T2D-parameters compared to non-migrants, but were less likely to meet HbA1c targets. This might partly reflect the less frequent insulin prescriptions to migrants. Further research is needed on underlying mechanisms and the specific needs of migrant groups to optimize T2D-care for all.</div></div>","PeriodicalId":48997,"journal":{"name":"Primary Care Diabetes","volume":"20 1","pages":"Pages 53-60"},"PeriodicalIF":2.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145310542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel anthropometric indices for predicting diabetes mellitus: A population-based study 预测糖尿病的新型人体测量指标：一项基于人群的研究

IF 2.3 4区医学 Q3 ENDOCRINOLOGY & METABOLISM

Primary Care Diabetes

Pub Date : 2026-02-01 Epub Date: 2025-10-25 DOI: 10.1016/j.pcd.2025.10.006

Fatemeh Baberi , Shayan Rezaeianzadeh , Abbas Rezaianzadeh , Andishe Hamedi

Aims

There is still no complete agreement on the best anthropometric index for identifying type 2 diabetes. This study aims to evaluate the predictive power of the novel indices compared with traditional and to better understand how gender influences this association.

Methods

Baseline data of the Kharameh cohort study, which includes Iranian adults between 40 and 70 years, were used in this cross-sectional study. Anthropometric indices such as BMI, WHR, WHtR, ABSI, BRI, and BAI were evaluated for identifying type 2 diabetes. Statistical analysis was performed using independent t-tests and logistic regression to examine the association of these indices with diabetes in men and women. ROC curves were calculated to determine the sensitivity and specificity of each index.

Results

Fifteen percent of our 10,663 participants had diabetes. Anthropometric indices were significantly higher in the diabetic group than in the non-diabetic group and were significantly associated with an increased risk of type 2 diabetes. WHR performed as the best in predicting diabetes, with an optimal cutoff point of WHR > 0.95 for both sexes. BMI and BAI were the least accurate, with AUCs of less than 60 % for both sexes.

Conclusions

The findings underscore the crucial role of body fat distribution, particularly central or abdominal obesity, in predicting diabetes risk. The use of anthropometric indices like WHR could be valuable in identifying individuals at high risk for type 2 diabetes, thereby aiding the development of effective screening and prevention programs.

目的对于识别2型糖尿病的最佳人体测量指数尚无完全一致的看法。本研究旨在评估新指标与传统指标相比的预测能力，并更好地了解性别如何影响这种关联。方法：这项横断面研究使用了Kharameh队列研究的基线数据，其中包括40至70岁的伊朗成年人。评估人体测量指标，如BMI、WHR、WHtR、ABSI、BRI和BAI，以识别2型糖尿病。采用独立t检验和logistic回归进行统计分析，以检验这些指标与男性和女性糖尿病的相关性。计算ROC曲线，确定各指标的敏感性和特异性。结果10663名参与者中有15%患有糖尿病。糖尿病组的人体测量指数明显高于非糖尿病组，并且与2型糖尿病风险增加显著相关。WHR在预测糖尿病方面表现最好，男女WHR的最佳临界值为 0.95。BMI和BAI是最不准确的，男女的auc都小于60% %。结论：研究结果强调了身体脂肪分布，特别是中腹部肥胖，在预测糖尿病风险方面的关键作用。使用像腰宽比这样的人体测量指标在识别2型糖尿病高危人群方面可能是有价值的，从而有助于制定有效的筛查和预防计划。

{"title":"Novel anthropometric indices for predicting diabetes mellitus: A population-based study","authors":"Fatemeh Baberi , Shayan Rezaeianzadeh , Abbas Rezaianzadeh , Andishe Hamedi","doi":"10.1016/j.pcd.2025.10.006","DOIUrl":"10.1016/j.pcd.2025.10.006","url":null,"abstract":"<div><h3>Aims</h3><div>There is still no complete agreement on the best anthropometric index for identifying type 2 diabetes. This study aims to evaluate the predictive power of the novel indices compared with traditional and to better understand how gender influences this association.</div></div><div><h3>Methods</h3><div>Baseline data of the Kharameh cohort study, which includes Iranian adults between 40 and 70 years, were used in this cross-sectional study. Anthropometric indices such as BMI, WHR, WHtR, ABSI, BRI, and BAI were evaluated for identifying type 2 diabetes. Statistical analysis was performed using independent t-tests and logistic regression to examine the association of these indices with diabetes in men and women. ROC curves were calculated to determine the sensitivity and specificity of each index.</div></div><div><h3>Results</h3><div>Fifteen percent of our 10,663 participants had diabetes. Anthropometric indices were significantly higher in the diabetic group than in the non-diabetic group and were significantly associated with an increased risk of type 2 diabetes. WHR performed as the best in predicting diabetes, with an optimal cutoff point of WHR > 0.95 for both sexes. BMI and BAI were the least accurate, with AUCs of less than 60 % for both sexes.</div></div><div><h3>Conclusions</h3><div>The findings underscore the crucial role of body fat distribution, particularly central or abdominal obesity, in predicting diabetes risk. The use of anthropometric indices like WHR could be valuable in identifying individuals at high risk for type 2 diabetes, thereby aiding the development of effective screening and prevention programs.</div></div>","PeriodicalId":48997,"journal":{"name":"Primary Care Diabetes","volume":"20 1","pages":"Pages 30-35"},"PeriodicalIF":2.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146098800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

下一页尾页

类型

全部化学•材料生命科学医学物理工程技术环境•农林材料科学地球科学法学管理学化学环境科学与生态学计算机科学教育学经济学农林科学人文科学生物学数学物理与天体物理心理学综合性期刊其他工业工程理学历史学农学文学信息工程

数据库

全部 ACS Publications Elsevier ieeexplore Springer The Royal Society of Chemistry Wiley

期刊

Primary Care Diabetes

全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.

﹀