T. Yoshizaki, Shinobu Minatani, Hiroto Namba, Akitoshi Takeda, J. Kawabe, Hideko Mizuta, Yasuhiro Wada, A. Mawatari, Yasuyoshi Watanabe, H. Shimada, Makoto Higuchi, Y. Itoh
{"title":"Tau accumulates differently in four subtypes of Alzheimer's disease","authors":"T. Yoshizaki, Shinobu Minatani, Hiroto Namba, Akitoshi Takeda, J. Kawabe, Hideko Mizuta, Yasuhiro Wada, A. Mawatari, Yasuyoshi Watanabe, H. Shimada, Makoto Higuchi, Y. Itoh","doi":"10.1111/ncn3.12715","DOIUrl":null,"url":null,"abstract":"Heterogeneity in Alzheimer's disease (AD) has been reported on the basis of clinical, neuropathological, and neuroimaging data. However, most of the indices, including cerebral atrophy evaluated using magnetic resonance imaging and amyloid β (Aβ) accumulation detected using positron emission tomography (PET), lack sensitivity, and specificity for categorization.","PeriodicalId":19154,"journal":{"name":"Neurology and Clinical Neuroscience","volume":null,"pages":null},"PeriodicalIF":0.4000,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neurology and Clinical Neuroscience","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/ncn3.12715","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Heterogeneity in Alzheimer's disease (AD) has been reported on the basis of clinical, neuropathological, and neuroimaging data. However, most of the indices, including cerebral atrophy evaluated using magnetic resonance imaging and amyloid β (Aβ) accumulation detected using positron emission tomography (PET), lack sensitivity, and specificity for categorization.
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