Manifestación clínica de la composición corporal en pacientes con síndrome de ovario poliquístico

Abstract

Polycystic ovary syndrome it is an endocrine-metabolic dysfunction and it is explained as a female functional hyperandrogenism. Associated to this, several systemic alterations are triggered, with one of these very important dysfunctions being the accumulation of visceral fat tissue. It has been demonstrated that the androgens and the increase of the free fatty acids, as observed in central type obesity, inhibit the hepatic action of insulin that results in compensatory hyperinsulinism secondary to insulin resistance. For this reason, patients with polycystic ovary syndrome present with diverse clinical, hormonal and metabolic characteristics, depending on their body fat and its distribution pattern. The classification into sub-groups can help to identify the systemic dysfunctions that each patient may have. One of these parameters is the phenotype associated with the body composition, which can be measured using the electrical impedance of the body fluids that helps to determine the distribution of the different components of the human body. For this reason, the study of the body composition should be now considered as part of the follow-up of patients with polycystic ovary syndrome, in order to determine the response to the treatments used in the correction of this systemic dysfunction.