Prevalence and risk factors for disability in leprosy patients in Indonesia during the post-elimination era.

IF 5.6 2区 医学 Q1 PHYSIOLOGY Acta Physiologica Pub Date : 2023-08-09 eCollection Date: 2023-12-01 DOI:10.4081/dr.2023.9777
Paula M Samosir, Presstisa Gifta Axelia, Firas F Alkaff, Sovia Salamah, Medhi Denisa Alinda
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Abstract

Leprosy has been nationally eliminated in Indonesia, but it continues to be a public health problem, with disability contributing to the disease burden. Disability caused by leprosy often results in stigmatization, leading to decreased quality of life. This was a retrospective cross-sectional study using secondary data from primary healthcare centers in one of the districts in the region with the highest number of leprosy patients in Indonesia. All leprosy patients between 2016-2022 were included. Among 189 leprosy patients (mean age 46 years old, 65.6% male), 19% had grade 1 disability and 29.6% had grade 2 disability. Duration of disease, nerve enlargements, leprosy reactions, and symmetric lesions were identified as risk factors for both grade 1 and 2 disability. Being male and having a positive smear test was associated with a higher risk of only grade 2 disability. Disability due to leprosy is still prevalent in the post-elimination era despite the decline in new leprosy cases. Improvement in early case detection and prevention of disability are still needed in the post-elimination era.

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消灭后时期印度尼西亚麻风病患者的患病率和致残风险因素
在印度尼西亚,麻风病已在全国范围内被消灭,但它仍然是一个公共卫生问题,残疾加剧了疾病负担。麻风病造成的残疾往往导致污名化,导致生活质量下降。这是一项回顾性横断面研究,使用来自印度尼西亚麻风病患者人数最多的地区之一的初级卫生保健中心的二级数据。2016-2022年期间的所有麻风病患者均被纳入。189例麻风患者(平均年龄46岁,65.6%为男性)中,19%为1级残疾,29.6%为2级残疾。疾病持续时间、神经增大、麻风病反应和对称病变被确定为1级和2级残疾的危险因素。男性和涂片检测呈阳性仅与2级残疾的高风险相关。尽管麻风病新发病例有所减少,但在消灭麻风病后的时代,因麻风病导致的残疾仍然普遍存在。在消除后时代,仍需要改进早期病例发现和残疾预防。
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来源期刊
Acta Physiologica
Acta Physiologica 医学-生理学
CiteScore
11.80
自引率
15.90%
发文量
182
审稿时长
4-8 weeks
期刊介绍: Acta Physiologica is an important forum for the publication of high quality original research in physiology and related areas by authors from all over the world. Acta Physiologica is a leading journal in human/translational physiology while promoting all aspects of the science of physiology. The journal publishes full length original articles on important new observations as well as reviews and commentaries.
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