{"title":"Keep the corners; adriamycin nephropathy","authors":"M. Momenzadeh","doi":"10.34172/npj.2022.10567","DOIUrl":null,"url":null,"abstract":"Implication for health policy/practice/research/medical education: Adriamycin is an anticancer agent with broad-spectrum efficacy against tumors. However, chemotherapy-induced renal toxicity constraints clinical efficacy of cancer treatment. The nephropathy of adriamycin is detected by podocyte damage and foot process effacement, which followed by glomerulosclerosis and inflammation in the tubulointerstitial area and fibrosis.","PeriodicalId":16388,"journal":{"name":"Journal of Nephropharmacology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Nephropharmacology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.34172/npj.2022.10567","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Implication for health policy/practice/research/medical education: Adriamycin is an anticancer agent with broad-spectrum efficacy against tumors. However, chemotherapy-induced renal toxicity constraints clinical efficacy of cancer treatment. The nephropathy of adriamycin is detected by podocyte damage and foot process effacement, which followed by glomerulosclerosis and inflammation in the tubulointerstitial area and fibrosis.
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