A Comprehensive Mini Review on the Natural Product Bacopa monnieri for the Management of Alzheimer’s Disease

IF 0.7 Q4 CHEMISTRY, MEDICINAL Natural Products Journal Pub Date : 2023-06-26 DOI:10.2174/2210315514666230626161007
Deepali Bansode, Naman Jain, Omkar Tambekar, Tanvi Goel, S. Bodhankar
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引用次数: 0

Abstract

Central nervous system disorders are expected to profoundly impact the global healthcare needs of the human community in this era. Senile decay of neurons is (Alzheimers Disease) AD. The hallmark of the pathophysiology of AD disease has two pivotal features: extracellular beta-amyloid deposition and intracellular tau hyperphosphorylation. New medicine-based psychoactive treatments have met with modest effectiveness due to the multifactorial nature of these diseases. As a result, there is an increasing need for new products that can address various receptors and enhance behavioral abilities independently or in tandem with traditional medications. Herbal products focused on conventional expertise have recently been widely popular in developed and developing countries. Ayurveda is a medical science that deals with the treatment of diseases using naturally occurring plant products. Ayurveda claims to have a large number of neuroprotective herbs. This review discusses the pharmacological effects and therapeutic properties of In-vivo, In-vitro, In-silico and human clinical trials of (Bacopa monnieri) BM against AD.
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天然产物假马齿苋治疗阿尔茨海默病的综合综述
在这个时代,中枢神经系统疾病预计将深刻影响人类社区的全球医疗保健需求。神经元的老年性衰退是(阿尔茨海默病)AD。阿尔茨海默病的病理生理学标志有两个关键特征:细胞外β -淀粉样蛋白沉积和细胞内tau过度磷酸化。由于这些疾病的多因素性质,新的基于药物的精神活性治疗效果一般。因此,对新产品的需求日益增加,这些新产品可以单独或与传统药物一起处理各种受体并增强行为能力。以传统专业知识为重点的草药产品最近在发达国家和发展中国家广泛流行。阿育吠陀是一门使用天然植物产品治疗疾病的医学科学。阿育吠陀声称有大量的神经保护草药。本文综述了假马齿苋(Bacopa monnieri) BM抗AD的体内、体外、计算机和人体临床试验的药理作用和治疗特性。
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来源期刊
Natural Products Journal
Natural Products Journal CHEMISTRY, MEDICINAL-
CiteScore
1.70
自引率
0.00%
发文量
91
期刊介绍: The Natural Products Journal a peer reviewed journal, aims to publish all the latest and outstanding developments in natural products. The Natural Products Journal publishes original research articles, full-length/mini reviews, letters and guest edited issues on all aspects of research and development in the field including: isolation, purification, structure elucidation, synthesis and bioactivity of chemical compounds found in nature.
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