Deepali Bansode, Naman Jain, Omkar Tambekar, Tanvi Goel, S. Bodhankar
{"title":"A Comprehensive Mini Review on the Natural Product Bacopa monnieri for the Management of Alzheimer’s Disease","authors":"Deepali Bansode, Naman Jain, Omkar Tambekar, Tanvi Goel, S. Bodhankar","doi":"10.2174/2210315514666230626161007","DOIUrl":null,"url":null,"abstract":"\n\nCentral nervous system disorders are expected to profoundly impact the global healthcare needs of the human community in this era. Senile decay of neurons is (Alzheimers Disease) AD. The hallmark of the pathophysiology of AD disease has two pivotal features: extracellular beta-amyloid deposition and intracellular tau hyperphosphorylation. New medicine-based psychoactive treatments have met with modest effectiveness due to the multifactorial nature of these diseases. As a result, there is an increasing need for new products that can address various receptors and enhance behavioral abilities independently or in tandem with traditional medications. Herbal products focused on conventional expertise have recently been widely popular in developed and developing countries. Ayurveda is a medical science that deals with the treatment of diseases using naturally occurring plant products. Ayurveda claims to have a large number of neuroprotective herbs. This review discusses the pharmacological effects and therapeutic properties of In-vivo, In-vitro, In-silico and human clinical trials of (Bacopa monnieri) BM against AD.\n","PeriodicalId":56153,"journal":{"name":"Natural Products Journal","volume":" ","pages":""},"PeriodicalIF":0.7000,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Natural Products Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/2210315514666230626161007","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
引用次数: 0
Abstract
Central nervous system disorders are expected to profoundly impact the global healthcare needs of the human community in this era. Senile decay of neurons is (Alzheimers Disease) AD. The hallmark of the pathophysiology of AD disease has two pivotal features: extracellular beta-amyloid deposition and intracellular tau hyperphosphorylation. New medicine-based psychoactive treatments have met with modest effectiveness due to the multifactorial nature of these diseases. As a result, there is an increasing need for new products that can address various receptors and enhance behavioral abilities independently or in tandem with traditional medications. Herbal products focused on conventional expertise have recently been widely popular in developed and developing countries. Ayurveda is a medical science that deals with the treatment of diseases using naturally occurring plant products. Ayurveda claims to have a large number of neuroprotective herbs. This review discusses the pharmacological effects and therapeutic properties of In-vivo, In-vitro, In-silico and human clinical trials of (Bacopa monnieri) BM against AD.
期刊介绍:
The Natural Products Journal a peer reviewed journal, aims to publish all the latest and outstanding developments in natural products. The Natural Products Journal publishes original research articles, full-length/mini reviews, letters and guest edited issues on all aspects of research and development in the field including: isolation, purification, structure elucidation, synthesis and bioactivity of chemical compounds found in nature.