MINIMALLY INVASIVE OPTICAL AND CYTOLOGICAL TECHNOLOGIES IN THE DIAGNOSTIC ALGORITHM FOR PATHOLOGICAL PROCESSES OF THE ORAL MUCOSA

Abstract

Despite scientific and technological progress and the emergence of modern diagnostic methods, the number of neglected cases of oncopathology has been increasing annually, and its mortality rate has been also increasing. Thus, over the past five years in Russia it increased by 12.4%. Moreover, the one-year mortality of patients with oral mucosa oncological pathology (OMC) is over 50 %, the 5-year survival rate is 24 % for men and 37 % for women. One of the demanded areas of effective medicine is the use of minimally invasive organ-preserving diagnostic tests, which unfortunately have not been widely used in practical dentistry. The purpose of the study is to improve early diagnostic efficiency for detecting pathological processes in the oral mucosa through the combined use of optical and cytological methods for its study. We examined 350 patients of both sexes aged from 20 to 67 years within consultation appointments with the aim of specifying the diagnosis and determining the algorithm of treatment. Methods: clinical, analytical, physical (autofluorescence dentistry), laboratory (liquid cytology), statistical. Conclusion: combined use of methods of autofluorescence stomatoscopy and liquid cytology increases efficiency of diagnostic stage, reduces risk of neglected stages of pathological processes, improves quality of patient's life.