Investigation of CO2 Extract of Portulaca oleracea for Antioxidant Activity from Raw Material Cultivated in Kazakhstan

IF 3 Q3 MATERIALS SCIENCE, BIOMATERIALS International Journal of Biomaterials Pub Date : 2022-04-22 DOI:10.1155/2022/6478977
Meruyert I Tleubayeva, R. Abdullabekova, U. Datkhayev, M. Ishmuratova, M. Alimzhanova, K. Kozhanova, Aida M. Seitaliyeva, K. Zhakipbekov, Zhanar Iskakova, E. Serikbayeva, E. Flisyuk
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引用次数: 1

Abstract

Medicinal plants remain as an important resource in the fight against many diseases, especially in developing countries. Antioxidants are substances capable of delaying, retarding, and preventing the oxidation of lipids or substances that delay or prevent free radical reactions during lipid oxidation. Natural antioxidants such as ascorbic acid, tocopherol, phenolic compounds, and flavonoids are a safe alternative to chemical antioxidants. In present work, results of antioxidant activity of raw materials from the cultivated plant Portulaca oleracea are presented. The extraction time was optimized to 780 minutes; the yield of extractive substances was 1.25% in the production of CO2 extract under subcritical conditions. For the first time, the antioxidant activity of Portulaca oleracea CO2 extract was determined by the amperometric method. Gas chromatography-mass spectrometry (GC-MS) chemical analysis of Portulaca oleracea CO2 extract dissolved in hexane revealed 37 components, including a complex mixture of aldehydes, alkanes, alkenes, esters, diterpenes, steroids, vitamin E, and carbohydrates. The investigation results showed that the Portulaca oleracea CO2 extract was promising for pharmaceutical, cosmetic, and food industries and had great potential for the prevention and treatment of diseases caused by oxidative stress.
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哈萨克马齿苋CO2萃取物抗氧化活性研究
药用植物仍然是防治许多疾病的重要资源,特别是在发展中国家。抗氧化剂是能够延缓、延缓和防止脂质氧化的物质,或者是在脂质氧化过程中延缓或防止自由基反应的物质。抗坏血酸、生育酚、酚类化合物和类黄酮等天然抗氧化剂是化学抗氧化剂的安全替代品。本文对马齿苋原料的抗氧化活性进行了研究。优化提取时间为780 min;在亚临界条件下生产CO2萃取物,萃取物得率为1.25%。首次采用安培法测定马齿苋CO2提取物的抗氧化活性。气相色谱-质谱联用(GC-MS)对马齿苋CO2萃取物进行化学分析,发现37种成分,包括醛类、烷烃、烯烃、酯类、二萜、类固醇、维生素E和碳水化合物的复杂混合物。研究结果表明,马齿苋CO2提取物在医药、化妆品、食品等行业具有广阔的应用前景,在防治氧化应激引起的疾病方面具有很大的潜力。
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来源期刊
International Journal of Biomaterials
International Journal of Biomaterials MATERIALS SCIENCE, BIOMATERIALS-
CiteScore
4.30
自引率
3.20%
发文量
50
审稿时长
21 weeks
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