Assessment of cyanide intake through consumption of cassava-based diets in the Democratic Republic of Congo

JSFA reports Pub Date : 2023-05-18 DOI:10.1002/jsf2.131
Christus C. Miderho, Lucy G. Njue, George O. Abong'
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Abstract

Background

Konzo is attributed to inadequate cassava processing and consumption of cassava meals with little protein, which is characterized by a neurological disorder that causes paralysis of the lower limbs. However, the exposure to cyanide in the Mwana health zone is still unknown while the prevalence of konzo is assumed to be high compared with other areas in the Democratic Republic of Congo (DRC).

Results

The results showed that women are the most affected (56.7%), followed by young people under the age of 10 (27%), and people from low socioeconomic class at 93.4%. The prevalence of konzo in Burhinyi is 0.06%. Cyanide intake by the population of Burhinyi ranged from 26 to 271 mg/kg bw/day at the 95th percentile through consumption of cassava-based ugali. Margin of exposure was around 0.271 and 0.393 g/person/day.

Conclusion

Poor people, women, and children are more at risk for konzo disease due to a diet dominated by under processed food made from cassava. However, since 2011, the study area's konzo prevalence has remained constant.

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在刚果民主共和国,通过食用以木薯为基础的饮食来评估氰化物摄入量
Konzo的发病原因是木薯加工不足和食用蛋白质含量低的木薯粉,其特点是导致下肢瘫痪的神经系统紊乱。然而,姆瓦纳卫生区接触氰化物的情况仍然未知,而假定与刚果民主共和国(刚果民主共和国)的其他地区相比,konzo的流行率很高。结果结果显示,受影响最大的是女性(56.7%),其次是10岁以下的青少年(27%),社会经济底层人群(93.4%)。konzo在Burhinyi的患病率为0.06%。在第95百分位数上,布希尼族人通过食用木薯制成的木薯粉摄入的氰化物为26至271毫克/公斤体重/天。暴露裕度分别为0.271和0.393 g/人/天。结论:穷人、妇女和儿童患konzo病的风险更大,因为他们的饮食主要是由木薯制成的加工不足的食品。然而,自2011年以来,研究区域的konzo患病率保持不变。
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