Optimum Treatment Planning Technique Evaluation For Synchronous Bilateral Breast Cancer With Left Side Supraclavicular Lymph Nodes

Q3 Health Professions Iranian Journal of Medical Physics Pub Date : 2020-11-09 DOI:10.22038/IJMP.2020.49211.1791
Sura Abdulkareem Madlool, S. S. Abdullah, H. Alabedi, Nabaa M. Alazawy, M. J. Al-Musawi, D. Saad, Ibrahim Al-nidawi, H. Ammar
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引用次数: 2

Abstract

Background: the Bilateral breast cancer cases are classified as a complex in radiotherapy treatment especially those with the left side mastectomy and right-side lumpectomy with left side supraclavicular lymph nodes patients. The purpose of this study is to find the optimum treatment planning technique among the three available techniques: 3D-CRT, IMRT, and VMAT.Materials and Methods: Ten Bilateral breast cancer included in this study with left side mastectomy and right-side lumpectomy with left side supraclavicular lymph nodes. The cross-sectional clinical study conducted in Baghdad ‎radiotherapy and nuclear medicine and Al-Andalus privet radiotherapy ‎hospital, Baghdad, Iraq. The patients are delineated by oncologists and prepare for radiation planning by MONACO 5.1 treatment planning system (TPS) with an X-ray photon beam of 6 MV or 10 MV energy using ‎ELEKTA‏’‏s Agility linear accelerator. The prescribed dose set at (4005 cCy per 15 fractions. Results: The treatment with 3D-CRT, IMRT, and VMAT show a significant difference in the results. VMAT give high dose distribution for the left mastectomy breast and it’s regional supraclavicular lymph nodes while the IMRT gives a higher value for the right side breast with lumpectomy. The good homogeneity index acquired with IMRT while VMAT gives a better conformity index. The 3D-CRT planning technique lowers the dose tho the heart and lunges better than the other techniques.Conclusion: Depending on the patient health and stage, the optimum treatment planning applied. Generally, VMAT is the optimum treatment planning technique for the studied group of SBBC patients. IMRT give effective coverage results better than the 3D-CRT.
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双侧同步乳腺癌伴左侧锁骨上淋巴结最佳治疗方案技术评价
背景:双侧乳腺癌在放射治疗中被归类为一个复杂的病例,尤其是左侧乳房切除术和右侧乳房肿瘤切除术合并左侧锁骨上淋巴结的患者。本研究的目的是在3D-CRT、IMRT和VMAT三种可用的技术中寻找最佳的治疗计划技术。材料和方法:本研究纳入10例双侧乳腺癌,左侧乳房切除术和右侧乳房肿瘤切除术合并左侧锁骨上淋巴结。在伊拉克巴格达的巴格达放射治疗和核医学以及Al-Andalus私立放射治疗医院进行的横断面临床研究。肿瘤学家对患者进行描述,并使用MONACO 5.1治疗计划系统(TPS)进行放射计划,使用ELEKTA的Agility线性加速器,使用6 MV或10 MV能量的x射线光子束。处方剂量设定为每15份4005ccy。结果:3D-CRT、IMRT、VMAT治疗效果有显著性差异。VMAT对左侧乳房及其锁骨上区域淋巴结的剂量分布较高,而IMRT对右侧乳房肿瘤切除术的剂量分布较高。IMRT获得较好的均匀性指标,VMAT获得较好的一致性指标。3D-CRT计划技术比其他技术更能降低对心脏和肺的剂量。结论:根据患者的健康状况和分期,制定最佳的治疗方案。一般情况下,VMAT是SBBC患者的最佳治疗计划技术。IMRT的有效覆盖效果优于3D-CRT。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Iranian Journal of Medical Physics
Iranian Journal of Medical Physics Health Professions-Radiological and Ultrasound Technology
CiteScore
1.00
自引率
0.00%
发文量
0
审稿时长
8 weeks
期刊介绍: Iranian Journal of Medical Physics (IJMP) is the official scientific bimonthly publication of the Iranian Association of Medical Physicists. IJMP is an international and multidisciplinary journal, peer review, free of charge publication and open access. This journal devoted to publish Original Papers, Review Articles, Short Communications, Technical Notes, Editorial and Letters to the Editor in the field of “Medical Physics” involving both basic and clinical research. Submissions of manuscript from all countries are welcome and will be reviewed by at least two expert reviewers.
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