Metrology and visualization analysis of literatures related to tumor immunotherapy based on CiteSpace

Abstract

To explore the development of global tumor immunotherapy in the past 20 years, and analyze the research status, hotspots and trends to provide theoretical support for subsequent research. CiteSpace 5.6.R2 software were used to analyze 290 articles related to tumor immunotherapy research from the Web of Science core data set from 2000 to 2019. CiteSpace was used to draw related visual maps and tables of coauthors, cooperating countries, cooperating institutions, literature and journal co‐citation, keyword co‐occurrence, and cluster analysis. The total amount of papers published in the field of tumor immunotherapy research has gradually increased. After receiving the Nobel Prize in Physiology or Medicine in 2018, the number of papers published in the field of research in tumor research reached 20. We found that the United States has the largest number of papers in all countries and China ranks 6. “Proceedings of the National Academy of Sciences of the United States of America,” “Journal of Immunology,” “Cancer Research,” “New England Journal of Medicine,” “Blood” is the top five core academic journals in this field. Cancer, disease, and tumor necrosis factor are the three keywords with the highest highlighting intensity. Comprehensive analysis shows that the coauthors, co‐institutions, and co‐cited journals of the literature are mostly concentrated in the United States. The rise of immunotherapy provides a new direction for tumor treatment. From 2018 to 2019, the number of literatures on tumor immunotherapy worldwide increased sharply. Immunotherapy combined with specific diseases is the current research frontier and hotspot.