Effect of Aqueous Extracts of Quercus resinosa on the Mechanical Behavior of Bigels

IF 2.3 Q3 PHARMACOLOGY & PHARMACY Scientia Pharmaceutica Pub Date : 2022-11-28 DOI:10.3390/scipharm90040073
J. Gallegos‐Infante, María del Pilar Galindo-Galindo, M. Moreno‐Jiménez, N. Rocha‐Guzmán, R. González-Laredo
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引用次数: 3

Abstract

Quercus resinosa leaves are rich in polyphenol compounds, however, they are unstable to several chemical and physical factors that limit their activity. Several methods have been developed to solve such problems, among which bigels can be mentioned and obtained using hydrogels and oleogels. The mechanical characterization of this type of materials is by using rheological methods. Although the use of these methods is well documented, the Carreau-Yasuda model has been little used to evaluate the effect of polyphenols on the mechanical behavior of bigels. Therefore, bigels were obtained from hydrogels (guar gum/xanthan gum, 0.5/0.5% w/v) and oleogels (sesame oil/sorbitan monostearate 10% w/w). Micrographs, linear viscoelasticity range, frequency sweep, and single shear tests were performed. The data were analyzed using ANOVA and Tukey test (p < 0.05); micrographs showed linear relationship between polyphenols concentration and droplet size. Liquid fraction of bigels showed a pseudoplastic behavior, while the parameters of Carreau-Yasuda model showed that the highest value of the complex viscosity at zero shear was at the lowest concentration of extract; the relaxation time presented the lowest value at higher concentrations of extracts. These results indicate that the presence of polyphenols modifyes the mechanical behavior of bigels.
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松香栎水提物对Bigels力学行为的影响
松皮栎叶含有丰富的多酚类化合物,但由于受到多种化学和物理因素的限制,其活性不稳定。为了解决这类问题,已经开发了几种方法,其中可以使用水凝胶和油凝胶来制备凝胶。这类材料的力学特性是通过流变学方法进行的。虽然这些方法的使用有很好的文献记载,但carau - yasuda模型很少用于评估多酚对bigels力学行为的影响。因此,从水凝胶(瓜尔胶/黄原胶,0.5/0.5% w/v)和油凝胶(芝麻油/山梨糖单硬脂酸10% w/w)中获得凝胶。显微照片,线性粘弹性范围,频率扫描和单剪切测试进行。数据分析采用方差分析和Tukey检验(p < 0.05);显微图显示多酚浓度与液滴大小呈线性关系。液体组分表现出假塑性行为,而carau - yasuda模型参数表明,零剪切时复合黏度的最大值出现在最低萃取物浓度时;提取物浓度越高,松弛时间越短。这些结果表明,多酚的存在改变了bigels的力学行为。
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来源期刊
Scientia Pharmaceutica
Scientia Pharmaceutica Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science
CiteScore
4.60
自引率
4.00%
发文量
67
审稿时长
10 weeks
期刊最新文献
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