Culture conditions for in vitro maturation of oocytes – A review

Mohammad Bahrami , Pauline A. Cottee
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引用次数: 6

Abstract

The maturation of oocytes external to the body is referred to IVM and is utilised by many different species. IVM bypasses traditional superovulation methods, where several hormonal injections are administered. Unfortunately, the pregnancy rates using IVM oocytes is less than those matured in vivo. This has impeded the uptake of the technology in ART laboratories. This review aims to explore the effects of multiple elements during IVM, discussing not only those which improve and impact on oocyte viability but those that can have deleterious effects on the oocyte.

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卵母细胞体外成熟的培养条件——综述
体外卵母细胞的成熟被称为体外卵母细胞成熟,被许多不同的物种利用。IVM绕过了传统的超排卵方法,在传统的超排卵方法中,需要注射几针激素。不幸的是,使用IVM卵母细胞的妊娠率低于体内成熟的卵母细胞。这阻碍了抗逆转录病毒治疗实验室采用该技术。本文旨在探讨多种因素在体外受精过程中的作用,不仅讨论了那些提高和影响卵母细胞活力的因素,还讨论了那些可能对卵母细胞产生有害影响的因素。
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