Determinants of Hypertension Treatment Adherence during the COVID-19 Pandemic: Lesson Learned from Various Studies Sites in Indonesia

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Abstract

Background: Hypertension is the most common comorbid disease which can cause further complications in COVID-19 patients. On the contrary, the pandemic has also caused lower health services and adherence to hypertension therapy. This study aimed to examine the impact of the COVID-19 pandemic on medication adherence in people with hypertension in Indonesia.Methods: The research was conducted using an analytical quantitative method. Patients with hypertension from seven islands across Indonesia were recruited based on eligibility criteria during Bulan Bakti 2021, a social outreach by Ikatan Senat Mahasiswa Kedokteran Indonesia about basic health across Indonesia. The demographic and medication history of the respondents were recorded. The Indonesian version of the Morisky Medication Adherence Scale (MMAS-8) questionnaire was distributed, and the medication adherence level was assessed.Results: A total of 1155 patients, mainly females (62.2%) participated in this study. More than half of the patients had low adherence (55.25%). Males (Adjusted Odd Ratio (AOR) 0.777 [CI 95% 0.529–1.019]), employed (AOR 0.857 [CI 95% 0.495–1.483]), higher income (AOR 0.522 [CI 95% 0.393–0.713]), and those who had information from healthcare worker (AOR 0.583 [CI 95% 0.361–0.878]) were found to have better medication adherence in multivariate logistic regression test.Conclusion: Medication adherence level in patients with hypertension during the pandemic is markedly low. Integrated preventive and promotive measures, especially from healthcare workers, are needed to prevent further morbidity and mortality. 
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COVID-19大流行期间高血压治疗依从性的决定因素:来自印度尼西亚各研究地点的经验教训
背景:高血压是COVID-19患者最常见的合并症,可导致进一步的并发症。相反,大流行病还造成保健服务减少和高血压治疗依从性降低。本研究旨在研究COVID-19大流行对印度尼西亚高血压患者药物依从性的影响。方法:采用分析定量方法进行研究。根据Bulan Bakti 2021期间的资格标准,招募了来自印度尼西亚七个岛屿的高血压患者,Bulan Bakti 2021是印度尼西亚Ikatan Senat Mahasiswa Kedokteran Indonesia关于印度尼西亚基本健康的社会外展活动。记录调查对象的人口统计学和用药史。发放印尼语版Morisky药物依从性量表(MMAS-8),并对患者的药物依从性进行评估。结果:共纳入1155例患者,以女性为主,占62.2%。超过一半的患者依从性较低(55.25%)。多因素logistic回归检验显示,男性(调整奇数比(AOR) 0.777 [CI 95% 0.529-1.019])、在职(AOR 0.857 [CI 95% 0.495-1.483])、高收入(AOR 0.522 [CI 95% 0.393-0.713])和有医护人员信息的患者(AOR 0.583 [CI 95% 0.361-0.878])具有更好的药物依从性。结论:大流行期间高血压患者的药物依从性明显较低。需要采取综合预防和促进措施,特别是卫生保健工作者的措施,以防止进一步的发病率和死亡率。
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审稿时长
20 weeks
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