Laboratory Study on the Repellent Bioefficacy of Diethyl Phenyl Acetamide (DEPA) against Aedes (Stegomyia) aegypti (Linnaeus)

C. Chen, O. Wan-Norafikah, K. W. Lau, H. Lee, C. Heo, C. Leong, M. Sofian‐Azirun
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Abstract

Insect repellent has played an important role in preventing humans from insect bites. This study was conducted to evaluate the repellency effect of a repellent cream containing 20% w/v diethyl phenyl acetamide (DEPA) against Aedes aegypti . DEET (10% w/v) was used as a standard repellent in comparison with DEPA. The test procedures followed the bioassay methods of Standards and Industrial Research Institute of Malaysia (SIRIM). There was statistically no significant difference between the repellency activity of both repellents (p>0.05), indicating the repellent cream of DEPA was as effective as DEET. Treatment with both repellent cream provided 8 hours of protection, with more than 60% reduction of mosquito landing on the skin.
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二乙基苯乙酰胺(DEPA)对埃及伊蚊(隐蚊)驱避生物药效的室内研究
驱虫剂在防止人类被昆虫叮咬方面发挥了重要作用。研究了含20% w/v二乙基苯乙酰胺(DEPA)的驱蚊膏对埃及伊蚊的驱蚊效果。避蚊胺(10% w/v)作为标准驱蚊剂,与DEPA进行比较。试验程序遵循马来西亚标准与工业研究所(SIRIM)的生物测定方法。两种驱蚊剂的驱蚊活性差异无统计学意义(p < 0.05),说明DEPA驱蚊膏的驱蚊效果与避蚊胺相同。用这两种驱蚊膏治疗可提供8小时的保护,减少60%以上的蚊子落在皮肤上。
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