An Interactive Framework for Teaching Viscoelastic Modeling

Delf Kah, B. Fabry, Richard C. Gerum
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Abstract

Rheologic models consisting of combinations of linear elements, such as springs and dashpots, are widely used in biophysics to describe the mechanical and, in particular, the viscoelastic behavior of proteins, cells, tissue, and soft matter. Even simple arrangements with few elements often suffice to recapitulate the experimental data and to provide biophysical insights, making them an ideal subject for educational purposes. To provide students with an intuitive understanding of the mechanical behavior of spring and dashpot models, we describe a computer simulation tool, elastic viscous system simulator (ElViS), written in the JavaScript programming language for designing viscoelastic models via a graphical user interface and simulating the mechanical response to various inputs. As an example application, we designed a virtual laboratory course using ElViS that teaches the basic principles of viscoelastic modeling in a gamelike manner. We then surveyed 50 undergraduate students of a 1-semester course in biophysics who participated in the virtual laboratory course. Students felt that the course was a helpful addition to the lecture and that it improved learning success.
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一个交互式的粘弹性建模教学框架
流变性模型由线性元素的组合组成,如弹簧和阻尼器,在生物物理学中被广泛用于描述力学,特别是蛋白质、细胞、组织和软物质的粘弹性行为。即使是很少元素的简单安排也足以概括实验数据,并提供生物物理学的见解,使它们成为教育目的的理想主题。为了让学生对弹簧和阻尼器模型的力学行为有一个直观的理解,我们描述了一个用JavaScript编程语言编写的计算机仿真工具,弹性粘性系统模拟器(ElViS),用于通过图形用户界面设计粘弹性模型并模拟各种输入的力学响应。作为一个示例应用程序,我们设计了一个虚拟实验室课程,使用ElViS以类似游戏的方式教授粘弹性建模的基本原理。然后,我们调查了50名参加虚拟实验室课程的生物物理学一学期课程的本科生。学生们觉得这门课是对讲课的有益补充,提高了学习的成功率。
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