Visual Function after Multifocal Intraocular Lens Insertion in a Heterozygous Granular Corneal Dystrophy Type 2 Patient: Case Report

J. H. Suh, Tae Hwan Kim, J. Choi, I. Jun, Sang Il Cho, E. Kim
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Abstract

Purpose: A patient with heterozygous granular corneal dystrophy type 2 (GCD2) underwent phacoemulsification with multifocal intraocular lens insertion, and complained of visual discomfort. We investigated the cause of the discomfort and visual function in this case.Case summary: A 59-year-old woman with granular opacity had slit lamp photographs taken 5 years earlier. Two years later, she underwent phacoemulsification with multifocal intraocular lens (Trifocal AT Lisa tri toric 839MP®, Carl Zeiss Meditec AG, Inc., Jena, Germany) insertion in both eyes at a local clinic. She felt very uncomfortable after the surgery, but the granular and lattice opacities due to GCD2 of her corneas remained stationary for 5 years. Her visual acuity decreased from preoperatively (preoperative: right 0.5, left 0.6; last visit: right 0.3, left 0.4). Her contrast sensitivity was also decreased and the total higher order aberration was increased (right 1.590 μm, left 1.194 μm), compared to normal range.Conclusions: Multifocal intraocular lens insertion in cataract surgery can lead to severe declines in contrast sensitivity and visual acuity and increased higher-order aberration in a GCD2 patient. It may not be advisable to use multifocal intraocular lenses in a GCD2 patient.
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杂合颗粒状角膜营养不良2型患者多焦点人工晶状体植入后的视觉功能:病例报告
目的:一名2型杂合颗粒性角膜营养不良(GCD2)患者接受了超声乳化白内障超声乳化多焦点人工晶状体植入术,并抱怨视觉不适。我们调查了这种情况下不适和视觉功能的原因。案例摘要:一名59岁的女性,颗粒不透明,5年前拍摄了裂隙灯照片。两年后,她在当地一家诊所接受了双眼多焦点人工晶状体超声乳化术(Trifocal AT Lisa tri-toric 839MP®,Carl Zeiss Meditec AG,股份有限公司,Jena,Germany)。手术后,她感到非常不舒服,但由于角膜GCD2导致的颗粒和晶格混浊在5年内保持静止。她的视力比术前下降(术前:右0.5,左0.6;最后一次就诊:右0.3,左0.4)。与正常范围相比,她的对比敏感度也下降,总高阶像差增加(右1.590μm,左1.194μm)。结论:白内障手术中的多焦点人工晶状体植入会导致GCD2患者的对比敏感度和视力严重下降,并增加高阶像差。在GCD2患者中使用多焦点人工晶状体可能是不可取的。
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