Oral lesions and associated factors in breast cancer survivors

Q1 Medicine Journal of Investigative and Clinical Dentistry Pub Date : 2019-08-12 DOI:10.1111/jicd.12447

Luísa Comerlato Jardim, Priscila Trindade Flores, Felipe de Araújo Sensever, Maria do Carmo dos Santos Araújo, Cristina Machado Bragança de Moraes, Juares Chiesa, Raquel Pippi Antoniazzi

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引用次数: 3

Abstract

Aim

To evaluate the prevalence of oral lesions (OL) and associated factors among survivors of breast cancer (BC).

Methods

A cross-sectional study involving 150 BC survivors was conducted at a public hospital in southern Brazil. Data were collected on socioeconomic aspects, treatment characteristics and oral problems. The decayed, missing and filled teeth index and the occurrence of OL were evaluated. Logistic regression was performed to determine independent variables associated with the outcome.

Results

24% of the women had at least 1 OL and 33.3% of these had more than one lesion. Melanotic macule was the most prevalent lesion. Duration of tamoxifen use, radiotherapy, missing teeth and xerostomia were associated with the occurrence of OL (P < .05). In the adjusted analysis, women with more than 13 missing teeth and xerostomia had 2.39-fold (95% confidence interval [CI], 1.06-5.40) and 2.71-fold (95% CI, 1.14-6.42), respectively, greater odds of exhibiting OL.

Conclusion

Approximately 1/4 of the BC survivors exhibited OL, which were associated with tooth loss and xerostomia. These findings could assist in the establishment of oral health strategies for women with BC.

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乳腺癌幸存者的口腔病变及相关因素

目的评估癌症幸存者口腔病变（OL）的患病率及其相关因素。方法在巴西南部一家公立医院对150名乳腺癌幸存者进行横断面研究。收集了有关社会经济方面、治疗特点和口腔问题的数据。评估蛀牙、缺牙和补牙指数以及OL的发生情况。进行Logistic回归以确定与结果相关的自变量。结果24%的女性至少有1个OL，33.3%的女性有一个以上的病变。黑色素性黄斑是最常见的病变。他莫昔芬的使用时间、放疗、缺牙和口干症与OL的发生有关（P＜0.05）。在调整后的分析中，缺牙和口干症超过13颗的女性表现出OL的几率分别为2.39倍（95%置信区间[CI]，1.06-5.40）和2.71倍（95%CI，1.14-6.42）。结论约1/4的BC幸存者表现出OL，其与牙齿缺失和口干症有关。这些发现可能有助于为患有BC的妇女制定口腔健康策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Investigative and Clinical Dentistry DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.90

自引率

0.00%

发文量

期刊介绍： Journal of Investigative and Clinical Dentistry (JICD) aims to publish quality, peer reviewed original research and topical reviews on all aspects of investigative and clinical dentistry and craniofacial research, including molecular studies related to oral health and disease. Although international in outlook, the Editor especially encourages papers from the Asia Pacific. The journal also aims to provide clinicians, scientists and students of dentistry with a knowledge transfer platform for rapid publication of reports through an international journal, which will be available free online until 2012. Its scope, therefore, is broad, inclusive and international, but with a particular focus on Asia Pacific. The Editor welcomes manuscripts in the following key thematic areas in oral and maxillofacial sciences: Community Dentistry and Oral Epidemiology, Conservative Dentistry, Dental Biomaterials, Dental Pedagogy, Endodontics and Traumatology, Implant Dentistry, Oral Biosciences, Oral and Maxillofacial Surgery, Oral Medicine, Oral Pathology and Oral Microbiology, Orthodontics, Oral Radiology, Oral Rehabilitation, Paedodontics, Periodontology and Periodontal Medicine.

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