Association of Leptin and Dried Fruit Mix and Nuts With Craving During Smoking Cessation

Thayzis d.P. Silva, A. S. Gomes, M. M. de Melo, T. M. de Oliveira, A. Galil, N. Percegoni, V. A. Fonseca, A. N. Bastos, A. S. de Aguiar
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Abstract

Objective: The objective of this study was to assess dried fruit mix and nuts and their effect on craving associated with the serum leptin of tobacco smokers. Materials and Methods: This is a clinical intervention study with a nonprobabilistic sample (n=23). The intervention group (IG) received 30 g of dried fruit and mix, and the control group (CG) received standard interventions. Test craving was analyzed using the Questionnaire of Smoking Urges (QSU-Brief). Serum leptin was assessed at the beginning and after 3 weeks. The data was tested using the SPSS program through the Shapiro-Wilk, unpaired Student t, or Mann-Whitney tests and multivariate linear regression. Results: The study showed significant difference between initial and final weights and body mass indices. The IG showed a high degree of smoking dependence. The IG showed reduced craving. In the CG, median serum leptin levels showed increased craving in the second and third weeks. Conclusions: Our results establish that craving decreased among smokers only in the IG. In the CG, above-median serum leptin levels reported a greater sense of pleasure in the second week. And in the third week, they experienced difficulties maintaining abstinence.
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瘦素、干果混合物和坚果与戒烟期间食欲的关系
目的:本研究的目的是评估干果混合物和坚果及其对烟草吸烟者血清瘦素相关渴求的影响。材料和方法:这是一项临床干预研究,使用了一个非概率样本(n=23)。干预组(IG)接受了30 g干果和混合物,对照组(CG)接受标准干预。使用吸烟欲望问卷(QSU Brief)对测试渴求进行分析。在开始和3周后评估血清瘦素。数据使用SPSS程序通过Shapiro-Wilk、未配对Student t或Mann-Whitney检验和多元线性回归进行测试。结果:研究显示,初始和最终体重以及体重指数之间存在显著差异。IG表现出高度的吸烟依赖性。IG表现出渴望减少。在CG中,血清瘦素水平中位数在第二周和第三周显示出渴望增加。结论:我们的研究结果表明,只有在IG中,吸烟者的渴望才会减少。在CG中,高于中位数的血清瘦素水平在第二周表现出更大的愉悦感。在第三周,他们在保持禁欲方面遇到了困难。
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期刊介绍: Addictive Disorders & Their Treatment is a quarterly international journal devoted to practical clinical research and treatment issues related to the misuses of alcohol and licit and illicit drugs and the study and treatment of addictive disorders and their behaviors. The journal publishes broad-spectrum, patient-oriented coverage of all aspects of addiction, directed toward an audience of psychiatrists, clinical psychologists, psychopharmacologists, and primary care practitioners. Original articles help clinicians make more educated, effective decisions regarding optimal patient management and care. In-depth reviews examine current understanding, diagnosis, and treatment of addiction disorders.
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