Experience of the drug utilization pattern of nonsteroidal anti-inflammatory drugs used in outpatient attendees (Patients) having osteoarthritis of a tertiary care hospital in central India

R. Siddiqui, Shadma H. Quazi, Sharjeel H. Khan, Tanaji R. Shende
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Abstract

Objective: The prime goal of prescription utilization study aims to facilitate patients' rational drug use for osteoarthritis (OA). OA being the commonest form of joint disease and the foremost cause of pain in aged people. The aim of this research was to offer feedback on the use of medicines for OA treatment. Methods: A 1-year prospective observational research conducted in collaboration with the orthopaedics department. 280 patients were enrolled satisfying the exclusion and inclusion conditions using the convenience sampling technique. Patients' data were recorded in the case report form and analysed. Results: Among 280 patients enrolled in the study, OA seemed to be more common in females as 53.5% of patients were females as compared to 45% of male patients. The most impacted age grouping in the study was 46–60 (60.7%) followed by 61–75 (30.7%). Aceclofenac and paracetamol are the most commonly used nonsteroidal antiinflammatory drugs in 29.6% of patients followed by a combination of diclofenac + paracetamol in 18.5%, etoricoxib in 16.7% and paracetamol and tramadol in combination in 8.2% of patients. Conclusions: In our study, it was seen that OA affects females more often than males and the knee joint being the commonly affected joint. Aceclofenac and paracetamol combination was the most the most preferred drug. Drug use research's main goal is to encourage communities to take medications responsibly. Drug prescribing studies seek to inform prescribers about the proper use of medications and to give them feedback for rational use of drugs.
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非甾体类抗炎药在印度中部一家三级医院骨关节炎门诊患者(患者)用药模式的经验
目的:促进骨关节炎(OA)患者合理用药是处方利用研究的首要目标。OA是最常见的关节疾病,也是老年人疼痛的主要原因。本研究的目的是为OA治疗药物的使用提供反馈。方法:与骨科合作进行的一项为期一年的前瞻性观察性研究。采用方便抽样技术对280名符合排除和纳入条件的患者进行了入组。患者的数据记录在病例报告表中并进行分析。结果:在280名参与研究的患者中,OA似乎在女性中更常见,53.5%的患者是女性,而男性患者的比例为45%。研究中受影响最大的年龄组是46–60岁(60.7%),其次是61–75岁(30.7%)。29.6%的患者最常用的非甾体抗炎药是阿西洛芬酸和扑热息痛,其次是18.5%的患者使用双氯芬酸+扑热息酚,16.7%的患者为依托ricoxib,8.2%的患者服用扑热息醇和曲马多。结论:在我们的研究中,OA对女性的影响比男性更大,膝关节是最常见的关节。Aceclofenac和扑热息痛的组合是最优选的药物。药物使用研究的主要目标是鼓励社区负责任地服药。药物处方研究旨在告知处方医生药物的正确使用,并为他们提供合理使用药物的反馈。
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