M. Salamoon, L. Assad, F. Ahmad, M. Kenj, M. Bachour
{"title":"Her-2/neu Status in Syrian Women with Breast Carcinoma: A Syrian Cohort Study of more than 10000 Cases","authors":"M. Salamoon, L. Assad, F. Ahmad, M. Kenj, M. Bachour","doi":"10.18689/mjcsr-1000109","DOIUrl":null,"url":null,"abstract":"Results and Discussion: 2013 patients were found to be Her-2 positive (+++) forming 19.4% of the studied group, 2000 (19.3%) were (++) equivocal. On the other hand, 62% of patients were Her-2 negative (0 and 1+) scores. A further investigation of the positive and equivocal groups was performed by FISH showing positive results as follows: 1815/2013 of the (3+ patients) and 1143/2000 of the (2+ patients) respectively. In other word 57% of the (++) group were found to be FISH positive versus 9% negative FISH results in the (+++) group.","PeriodicalId":92819,"journal":{"name":"Madridge journal of cancer study & research","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Madridge journal of cancer study & research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18689/mjcsr-1000109","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Results and Discussion: 2013 patients were found to be Her-2 positive (+++) forming 19.4% of the studied group, 2000 (19.3%) were (++) equivocal. On the other hand, 62% of patients were Her-2 negative (0 and 1+) scores. A further investigation of the positive and equivocal groups was performed by FISH showing positive results as follows: 1815/2013 of the (3+ patients) and 1143/2000 of the (2+ patients) respectively. In other word 57% of the (++) group were found to be FISH positive versus 9% negative FISH results in the (+++) group.