Her-2/neu Status in Syrian Women with Breast Carcinoma: A Syrian Cohort Study of more than 10000 Cases

M. Salamoon, L. Assad, F. Ahmad, M. Kenj, M. Bachour
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Abstract

Results and Discussion: 2013 patients were found to be Her-2 positive (+++) forming 19.4% of the studied group, 2000 (19.3%) were (++) equivocal. On the other hand, 62% of patients were Her-2 negative (0 and 1+) scores. A further investigation of the positive and equivocal groups was performed by FISH showing positive results as follows: 1815/2013 of the (3+ patients) and 1143/2000 of the (2+ patients) respectively. In other word 57% of the (++) group were found to be FISH positive versus 9% negative FISH results in the (+++) group.
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叙利亚妇女乳腺癌的Her-2/ new状态:一项超过10000例的叙利亚队列研究
结果与讨论:2013例Her-2阳性(+++)占研究组的19.4%,2000例(+++)模棱两可(19.3%)。另一方面,62%的患者Her-2阴性(0和1+)。FISH对阳性组和模棱两可组进行进一步调查,阳性结果分别为(3+患者)1815/2013和(2+患者)1143/2000。换句话说,57%的(++)组被发现为FISH阳性,而(+++)组的FISH阴性结果为9%。
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