Evaluation of Clinical, Demographic, and Biochemical Profiles of Trinidadian Patients Undergoing Coronary Angiography

S. Nayak B, T. Monplaisir, Geetha Bhaktha, R. Ali, S. Mohan, V. Priya
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Abstract

Abstract Background  Trinidad and Tobago ranks number 45 in the world for total deaths due to coronary heart disease. Predictive tests for coronary angiographic results set the basis for earlier monitoring of the disease before additional complications become obvious. Aims and Methods  This study aimed to evaluate the anthropometric and biochemical parameters of 124 patients with suspected coronary artery disease (CAD) in Trinidad and how these parameters correlate to the findings at angiography. Results  The biochemical parameters showed statistically significant correlations with CAD severity by Spearman's rank-order correlation. Two clinical parameters showed significant associations with CAD severity—ethnicity (χ 2 (4) = 12.925, p  = 0.012) and presence of type 2 diabetes at baseline (χ 2 (4) = 21.483, p  < 0.001). Conclusion  Biochemical parameters such as fasting blood sugar, N-terminal pro B-type natriuretic peptide, creatinine, and hemoglobin A1c were well correlated and well associated with the severity of CAD after diagnosis by the process of coronary angiography. Hence, these factors can be taken into consideration to predict the severity of CAD.
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评估特立尼达患者接受冠状动脉造影的临床、人口统计学和生化特征
摘要背景 特立尼达和多巴哥因冠心病死亡的总人数居世界第45位。冠状动脉造影结果的预测性测试为在其他并发症明显之前早期监测疾病奠定了基础。目标和方法 本研究旨在评估特立尼达124名疑似冠状动脉疾病(CAD)患者的人体测量和生化参数,以及这些参数与血管造影结果的相关性。后果 通过Spearman秩序相关,生化参数与CAD严重程度具有统计学显著相关性。两个临床参数显示与CAD严重程度显著相关——种族(χ2(4) = 12.925,p = 0.012)和基线时是否存在2型糖尿病(χ2(4) = 21.483,p < 0.001)。结论 通过冠状动脉造影诊断后,空腹血糖、N-末端B型钠尿肽原、肌酐和血红蛋白A1c等生化参数与CAD的严重程度密切相关。因此,可以考虑这些因素来预测CAD的严重程度。
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审稿时长
12 weeks
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