{"title":"Growth rate, growth curve and growth prediction of tumour in the competitive model","authors":"Mahdi Sohrabi-Haghighat, Atefeh Deris","doi":"10.1080/13873954.2020.1738498","DOIUrl":null,"url":null,"abstract":"ABSTRACT The growth of cancer is still the focus of many research works in the scientific community. So far, various models have been introduced to analyse the behaviour of cancers, including the mathematical growth models such as Logistic, Gompertz and Bertalany. Despite the advances in the analysis of the cancer behaviour, the lack of definitive treatment of cancer disease indicates the need for new perspectives which are supported by more biological background. Recently, a model has been proposed, in which, the tumour growth is interpreted as the outcome of the competition of healthy and cancer cells over the available oxygen, nutrients and space. We have modified this model in order to provide the necessary preparations for wider use of the model in growth rate, growth curve and growth prediction of tumours. Meanwhile, the model is performed on some experimental data to show its capabilities.","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2020-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13873954.2020.1738498","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"100","ListUrlMain":"https://doi.org/10.1080/13873954.2020.1738498","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
ABSTRACT The growth of cancer is still the focus of many research works in the scientific community. So far, various models have been introduced to analyse the behaviour of cancers, including the mathematical growth models such as Logistic, Gompertz and Bertalany. Despite the advances in the analysis of the cancer behaviour, the lack of definitive treatment of cancer disease indicates the need for new perspectives which are supported by more biological background. Recently, a model has been proposed, in which, the tumour growth is interpreted as the outcome of the competition of healthy and cancer cells over the available oxygen, nutrients and space. We have modified this model in order to provide the necessary preparations for wider use of the model in growth rate, growth curve and growth prediction of tumours. Meanwhile, the model is performed on some experimental data to show its capabilities.
期刊介绍：
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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