Starch Modified Tough Biocompatible Polyurethane/acrylamide bio Composites: Physicochemical Properties and Biodegradation Studies

Abstract

Biodegradable bio composites with potential applications in medical implants were prepared with starch content by in situ polymerization technique using polyurethane prepolymers. (PU) and acrylamide (AAM) monomers. The structure and properties of bio composites were evaluated. FT-IR spectroscopy showed bonding between N=C=O functional group terminated polyurethanes confirmed improved compatibility of prepolymers, AAM, starch and bio composites. The DSC data are the glass transition (Tg) of the bio composite and ordinary polyacrylamide (PAAM) network. By incorporating starch and polyurethane in the form of an interpenetrating network into a polyacrylamide network, mechanical and thermal properties of bio composites due to higher crosslink density given by hard segment content. We studied the swelling behavior of both bio composites and individual PAAM networks under different pH conditions to validate their biocompatibility and potential use in biomedicine setting. The hydrolytic stability of biocomposites and PAAM networks was investigated using phosphate buffer. Hydrolytic stability of biocomposites was found to be higher comparison with PAAM network. Morphological analysis of the samples showed uniform distribution and good interfacial adhesion. Improves sample biodegradability it was revealed by the soil runoff test.