Evaluación de la eficacia clínica de tres protocolos antibióticos en yeguas diagnosticadas con endometritis bacteriana

Abstract

Bacterial endometritis is one of the most common causes of reproductive failure in mares, generally associated with bacterial agents such as Streptococcus equi, Echerichia coli, Enterococcus spp, Klebsiella sp., Among others. Antimicrobial therapies based on beta-lactam drugs and aminoglycosides infiltrated at the uterine level or in systemic therapy are commonly used. The main objective of this study is to evaluate the clinical efficacy of three antibiotic protocols in mares with a diagnosis of bacterial endometritis and to verify their post-treatment reproductive performance. The sample was made with 90 mares diagnosed with uterine infection. By reproductive clinical examination, vaginoscopy and ultrasound. Uterine culture samples were taken by means of swabbing, in turn an antibiogram was performed. The mares were divided into three antibiotic treatment groups assigned according to the antibiogram results: procaine penicillin G (n = 4), ceftiofur (n = 10) and gentamicin (n = 20). Subsequently, the clinical efficacy and reproductive performance of the mares were evaluated. Of those treated with penicillin, 75% (3/4) recovered and two became pregnant; of those treated with gentamicin, 75% (15/20) recovered and 8 became pregnant; while of those treated with ceftiofur, 70% (7/10) recovered and 5 had pregnancy confirmed. It is concluded there were no post-treatment clinical or reproductive differences due to the type of antibiotic used.