A systematic review, meta-analysis and economic evaluation on Neonatal cpap

Q2 Mathematics Computational and Mathematical Biophysics Pub Date : 2022-01-01 DOI:10.1515/cmb-2022-0133

R. Keerthan, P. Nagaseshu, G. Gopalan, K. Kachroo, Jitendra Sharma

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Abstract

Abstract The review mainly focuses on the goals to evaluate the clinical and cost effectiveness of neonatal CPAP in a decrease of Mortality, Length of Stay, Respiratory support, Extubation and Intubation. Introduction: Inclusion criteria: This review is conducted in neonates with respiratory failure, Pneumonia sepsis, necrotizing infections, Pneumothorax, Broncho pulmonary distress, respiratory distress syndrome (RDS), COVID-19, and other comorbidities also included. Methods: The databases like PubMed, Google Scholar, and Cochrane were used in this review. Depending on inclusion criteria the full-text articles were assessed and chosen studies were recovered by methodological quality. Results: one twenty-six studies are retrieved which met the inclusion criteria and the extracted studies were pooled statistically and their outcomes were measured. All the studies explain the efficacy of CPAP by reducing Mortality, Length of Stay, Respiratory support, Extubation and Intubation. Conclusion: Currently the evidence states that CPAP reduces Mortality, Length of Stay, Respiratory support, Extubation and Intubation

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新生儿cpap的系统回顾、荟萃分析和经济评价

摘要本综述旨在评价新生儿CPAP在降低死亡率、住院时间、呼吸支持、拔管和插管等方面的临床和成本效益。纳入标准:本综述纳入了伴有呼吸衰竭、肺炎败血症、坏死性感染、气胸、支气管肺窘迫、呼吸窘迫综合征(RDS)、COVID-19以及其他合并症的新生儿。方法:本综述使用PubMed、谷歌Scholar、Cochrane等数据库。根据纳入标准对全文文章进行评估，并根据方法学质量对所选研究进行检索。结果:检索到符合纳入标准的1 26项研究，对提取的研究进行统计汇总并测量其结果。所有的研究都通过降低死亡率、住院时间、呼吸支持、拔管和插管来解释CPAP的疗效。结论:目前的证据表明，CPAP降低死亡率，住院时间，呼吸支持，拔管和插管

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