Characteristics, microorganism, and antibiotic profile of patients with Fournier’s gangrene in a tertiary care centre in Indonesia: A retrospective analysis of 43 cases

Jeremy Thompson Ginting, G. A. Irdam
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Abstract

Background: Fournier’s gangrene (FG) is a fatal condition that often leads to death if not treated properly. To this date, there are no data regarding FG in Indonesia. Objective: This study aims to investigate the characteristics of patients with FG.Methods: A cross-sectional study design was used to evaluate the medical records of patients admitted to Cipto Mangunkusumo Hospital between January 2012 and December 2017.Results: The median age of the subjects were 51 (2-81) years. All of the subjects were male and presented with scrotal pain. The scrotal abscess was found in 38 (88.4%) cases. Type II diabetes was found in 10 (23.3%) subjects. E. coli was the most dominant causative agent in 28 (65.1%) cases. Meropenem was administered in 16 (37.2%) subjects, and 16 (37.2%) subjects had antibiotics administered for ≤7 days. Conclusion: Although the mortality rate has decreased, those with FG tend to have a long hospital stay, which implies a high risk of complications. All males presenting with scrotal pain should be suspected of FG. Further studies on long-term hospitalisation complications in those with FG are required.
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印度尼西亚三级保健中心富尼耶坏疽患者的特征、微生物和抗生素谱:对43例病例的回顾性分析
背景:富尼耶坏疽(FG)是一种致命的疾病,如果治疗不当往往会导致死亡。到目前为止,没有关于印度尼西亚FG的数据。目的:探讨FG患者的特点。方法:采用横断面研究设计,对2012年1月至2017年12月在Cipto Mangunkusumo医院住院的患者病历进行评估。结果:患者年龄中位数为51(2 ~ 81)岁。所有受试者均为男性,表现为阴囊疼痛。阴囊脓肿38例(88.4%)。2型糖尿病10例(23.3%)。28例(65.1%)以大肠杆菌为主。16例(37.2%)患者使用美罗培南,16例(37.2%)患者使用抗生素≤7天。结论:虽然死亡率有所下降,但FG患者住院时间较长,并发症风险较高。所有出现阴囊疼痛的男性都应怀疑FG。需要进一步研究FG患者的长期住院并发症。
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