{"title":"Research progress of non-coding RNA in hepatic ischemia-reperfusion injury","authors":"Shilong Zhang, Zanjie Feng, Cijun Peng, Weidong Gao, Yuling Duan, Guoxin Fan","doi":"10.3760/CMA.J.ISSN.1007-8118.2020.01.019","DOIUrl":null,"url":null,"abstract":"Hepatic ischemia-reperfusion injury (HIRI) is the main cause of liver damage and even multiple organ failure after complex liver surgery. When liver ischemia reperfusion occurs, the non-coding RNAs in the liver tissue is dysregulated and part of the non-coding RNAs with abnormal expression is involved in HIRI regulation. Non-coding RNAs to may be the intervention target for reducing HIRI. This article summarized the types and related functions of non-coding RNAs, the role of different non-coding RNAs in HIRI, and the interconnections between various non-coding RNAs in HIRI. \n \nKey words: \nReperfusion injury; Liver; Non-coding RNA; MicroRNA; Small interfering RNA","PeriodicalId":10021,"journal":{"name":"中华肝胆外科杂志","volume":"26 1","pages":"72-75"},"PeriodicalIF":0.0000,"publicationDate":"2020-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华肝胆外科杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1007-8118.2020.01.019","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Hepatic ischemia-reperfusion injury (HIRI) is the main cause of liver damage and even multiple organ failure after complex liver surgery. When liver ischemia reperfusion occurs, the non-coding RNAs in the liver tissue is dysregulated and part of the non-coding RNAs with abnormal expression is involved in HIRI regulation. Non-coding RNAs to may be the intervention target for reducing HIRI. This article summarized the types and related functions of non-coding RNAs, the role of different non-coding RNAs in HIRI, and the interconnections between various non-coding RNAs in HIRI.
Key words:
Reperfusion injury; Liver; Non-coding RNA; MicroRNA; Small interfering RNA
期刊介绍：
Chinese Journal of Hepatobiliary Surgery is an academic journal organized by the Chinese Medical Association and supervised by the China Association for Science and Technology, founded in 1995. The journal has the following columns: review, hot spotlight, academic thinking, thesis, experimental research, short thesis, case report, synthesis, etc. The journal has been recognized by Beida Journal (Chinese Journal of Humanities and Social Sciences).
Chinese Journal of Hepatobiliary Surgery has been included in famous databases such as Peking University Journal (Chinese Journal of Humanities and Social Sciences), CSCD Source Journals of China Science Citation Database (with Extended Version) and so on, and it is one of the national key academic journals under the supervision of China Association for Science and Technology.
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