Agreement of Ocular Biometry Measured by LenStar LS 900 and CASIA2 Optical Coherence Tomography

Abstract

Introduction:The present study aimed to compare the anterior segment measurements between optical low-coherence reflectometry (LenStar LS900) and anterior segment optical coherence tomography (CASIA2 OCT). Methods:A total of 198 right eyes of 198 healthy participants were used for the current study, according to the inclusion and exclusion criteria. Ocular biometry parameters, such as central corneal thickness (CCT), anterior chamber depth (ACD), keratometry, and anterior chamber width (ACW), were measured usingLenStar LS 900 and CASIA2 OCT. The differences and correlations were assessed between these two instruments. The agreement was calculated as the 95% limits of agreement (LoA). Results: Among 198 subjects with a mean age of 29.39±7.88 years who enrolled in the study, 106 individuals (53.5%) were women. The mean CCT values were 531.7±35.25 and 527.3±37.82 µm for LenStar and OCT, respectively (P˂0.0001). The ACD measurements showed 2.92±0.40 and 2.95±0.43 mm for LenStar and OCT, respectively (P=0.0549). The ACW mean values were 12.04±0.52 and 11.79±0.49 mm by LenStar and OCT (P˂0.0001). The 95% LoA between the two instruments were within the ranges of -20.79 to 29.43 µm, -0.50 to -0.43 mm, -0.32 to 0.82 mm, and -0.70 to 0.87 D for CCT, ACD, ACW, and astigmatism, respectively. Conclusion: LenStar and OCT showed to have interchangeable ACD measurements; however, the results of CCT, ACW, and corneal astigmatism measured by these two instruments demonstrated clinically significant differences