A Review of CRP as a Biomarker of COVID-19

Farzana Binte Abedin Leera, M. Rahman
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Abstract

The outbreak of coronavirus disease 2019 (COVID_19) is an emerging global health threat. The healthcare workers are facing challenges in reducing the severity and mortality across the world. Patients with severe form of COVID_19 are generally treated in the intensive care unit, while mild or non_severe patients are treated in the isolation ward or at home. It is important to identify early and give treatment to reduce the disease severity and improve the outcomes. There is no credible and convenient biomarker to predict the severity of the disease. Therefore, the exploration of biomarkers is deemed necessary. We aimed to review the diagnostic and early prognostic value of C-reactive protein (CRP) in COVID-19 patients. In a number of studies, CRP showed different distribution feature and differences existed in various ages, clinical types and outcomes of COVID-19 patients. The present study reviews the role of CRP level as a marker in indicating the severity of patients with COVID_19. Delta Med Col J. Jul 2020 8(1): 41-45
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CRP作为COVID-19生物标志物的研究进展
2019冠状病毒病(COVID_19)的爆发是一个新出现的全球健康威胁。医护人员在降低世界各地的严重程度和死亡率方面面临挑战。重症新冠肺炎患者通常在重症监护室接受治疗,而轻症或非重症患者则在隔离病房或家中接受治疗。早期发现并给予治疗以降低疾病的严重程度并改善结果是很重要的。目前还没有可靠和方便的生物标志物来预测疾病的严重程度。因此,生物标志物的探索被认为是必要的。我们旨在回顾C-反应蛋白(CRP)在新冠肺炎患者中的诊断和早期预后价值。在多项研究中,CRP表现出不同的分布特征,在不同年龄、临床类型和结果的新冠肺炎患者中存在差异。本研究综述了CRP水平作为指示COVID_19患者严重程度的标志物的作用。德尔塔医学杂志2020年7月8(1):41-45
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审稿时长
20 weeks
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