Resultados maternos y neonatales de trillizos nacidos por diferentes métodos de embarazo

M.A. Guido Campuzano , L.A. Fernández Carrocera , T. Sandoval Hernández , P. García Alonso-Themann
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Abstract

Background

The incidence of multiple pregnancies has been increasing steadily for more than 30 years. The aim of this study is to analyse the clinical outcomes of mothers and triplets born by different pregnancy methods.

Material and methods

A longitudinal, observational, and analytical study conducted on a cohort of triplets born from January 2000 to December 2010.

Results

The analysis included a total of 82 sets of triplets, 246 (100%) neonates, with 12 (4.8%) deaths. The distribution of pregnant women according to the method was: 28 (34.1%) spontaneous pregnancies, 20 (24.3%) ovulation inducers 13 (15.8%), artificial insemination, and 21 (25.6%) by IVF-ET. The most frequent pathologies, in general, of all pregnancies were urinary tract infection 13.4%. The mean gestational age was 32.6 ± 1.7, range 25-36. The mean weight was 1561.52 ± 271.6, range 620-2460 g. Although intrauterine growth retardation occurred in 34% of all methods, there was no statistical difference. Respiratory disease was present in 34.6% of the total sample, with a statistical difference, P=.00014, respiratory distress syndrome was present in all methods P=.00014. Sepsis for the entire sample was 23.5%, and was distributed evenly for all methods. Only 2 cases of enterocolitis 2A were seen.

Conclusion

The highest percentage of pregnancies was spontaneous. All neonates were premature with low birth weight <2500 g. Respiratory problems (RDS, TTNB, and PAS) were statistically significant.

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不同怀孕方法所生三胞胎的母婴结果
30多年来,多胎妊娠的发生率一直在稳步上升。本研究的目的是分析不同妊娠方式出生的母亲和三胞胎的临床结果。材料与方法对2000年1月至2010年12月出生的三胞胎进行了一项纵向、观察和分析研究。结果共纳入82对三胞胎,新生儿246例(100%),死亡12例(4.8%)。按方法计算的孕妇分布为:自然妊娠28例(34.1%),促排卵20例(24.3%),人工授精13例(15.8%),IVF-ET 21例(25.6%)。总的来说,所有妊娠中最常见的病理是尿路感染,占13.4%。平均胎龄32.6±1.7,范围25 ~ 36。平均体重为1561.52±271.6,范围为620 ~ 2460 g。虽然有34%的方法发生了宫内生长迟缓,但没有统计学差异。呼吸道疾病占总样本的34.6%,差异有统计学意义,P=。00014,所有方法均存在呼吸窘迫综合征,P=.00014。脓毒症在整个样本中占23.5%,在所有方法中分布均匀。2A型小肠结肠炎2例。结论自然妊娠率最高。所有新生儿均为早产儿,出生体重低于2500克。呼吸问题(RDS、TTNB和PAS)有统计学意义。
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来源期刊
自引率
0.00%
发文量
24
审稿时长
20 weeks
期刊介绍: Perinatología y Reproducción Humana is the official journal of the Instituto Nacional de Perinatología, Mexico. It is aimed at physicians of the area of perinatal and reproductive health (obstetrics and gynecology, maternal and fetal medicine, pediatricians, neonatologists, endocrinologists, infectious disease specialists, and neurologists) and also at health sciences professionals involved in the study of reproduction perinatal and reproductive health (chemists, biologists and neuro-physiologists). It is an electronic biannual journal, that publishes peer-reviewed original articles, in-deep reviews, letters to the editor and special sections related to basic, epidemiological, surgical, and clinical aspects in the area of perinatal and reproductive health, in English or Spanish languages and open access.
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