Hemolytic Anemia and Hypoxic Brain Injury following Mothball Ingestion in a G6PD Nondeficient Infant: A Case Report

IF 0.3 Q4 PEDIATRICS Journal of Child Science Pub Date : 2021-01-01 DOI:10.1055/s-0041-1736477
S. Nongrum, Anuragsingh Chandel, R. Varma, S. Jategaonkar, Manish Jain
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Abstract

Mothballs are a common household item used as repellents and deodorizers. They are potential hazards and rare agents of poisoning in children. They are composed mainly of naphthalene, camphor, and 1, 4-dichlorobenzene in varying amounts depending on the manufacturers. It is essential to rule out poisoning by naphthalene in children presenting with hemolysis by eliciting a proper history. Since mothballs are readily available at home, children are drawn to it because of its attractive color and its consumption is a likely possibility. This is a case of ingestional naphthalene poisoning in a 1-year-old glucose 6-phosphate dehydrogenase nondeficient male child who presented with altered sensorium and hemolytic anemia. The child developed methemoglobinemia and sustained hypoxic brain injury. He was successfully managed by oral ascorbic acid, blood transfusion, and requisite supportive treatments. We report a case of naphthalene toxicity with hemolytic anemia and hypoxic brain damage to highlight the possibility of naphthalene poisoning in young children presenting with hemolytic anemia.
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无G6PD缺陷婴儿误食樟脑后溶血性贫血和缺氧脑损伤1例报告
樟脑丸是一种常见的家庭用品,用作驱虫剂和除臭剂。它们是儿童中毒的潜在危险和罕见因素。它们主要由萘、樟脑和1,4 -二氯苯组成,含量因制造商而异。有溶血症状的儿童有必要通过询问适当的病史来排除萘中毒。由于樟脑丸在家里很容易买到,孩子们被它吸引是因为它有吸引力的颜色,而且它很可能被吃掉。这是一例1岁的葡萄糖6-磷酸脱氢酶不缺乏的男孩,他表现为感觉改变和溶血性贫血。这名儿童出现了高铁血红蛋白血症和持续的缺氧脑损伤。通过口服抗坏血酸,输血和必要的支持治疗,他成功地控制了病情。我们报告一例萘中毒与溶血性贫血和缺氧脑损伤,以突出萘中毒的可能性,在年幼的儿童表现为溶血性贫血。
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