{"title":"A minimal model coupling communicable and non-communicable diseases","authors":"M. Marvá, E. Venturino, Carmen Vera","doi":"10.1051/mmnp/2023026","DOIUrl":null,"url":null,"abstract":"This work presents a model combining the simplest communicable and non-communicable disease models. The latter is, by far, the leadingn cause of sickness and death in the World, and introduces basal heterogeneity in populations where communicable diseases evolve. The model can be interpreted as a risk-structured model, another way of accounting for population heterogeneity.\nOur results show that considering the non-communicable disease (in the end, heterogeneous populations) allows the communicable disease to become endemic even if the basic reproduction number is less than $1$. This feature is known as subcritical bifurcation. Furthermore, ignoring the non-communicable disease dynamics results in overestimating the reproduction number and, thus, giving wrong information about the actual number of infected individuals. We calculate sensitivity indices and derive interesting epidemic-control information.","PeriodicalId":2,"journal":{"name":"ACS Applied Bio Materials","volume":null,"pages":null},"PeriodicalIF":4.6000,"publicationDate":"2023-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Bio Materials","FirstCategoryId":"100","ListUrlMain":"https://doi.org/10.1051/mmnp/2023026","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, BIOMATERIALS","Score":null,"Total":0}
引用次数: 0
Abstract
This work presents a model combining the simplest communicable and non-communicable disease models. The latter is, by far, the leadingn cause of sickness and death in the World, and introduces basal heterogeneity in populations where communicable diseases evolve. The model can be interpreted as a risk-structured model, another way of accounting for population heterogeneity.
Our results show that considering the non-communicable disease (in the end, heterogeneous populations) allows the communicable disease to become endemic even if the basic reproduction number is less than $1$. This feature is known as subcritical bifurcation. Furthermore, ignoring the non-communicable disease dynamics results in overestimating the reproduction number and, thus, giving wrong information about the actual number of infected individuals. We calculate sensitivity indices and derive interesting epidemic-control information.