Carcinoma de células pequeñas extrapulmonar de mama. Reporte de caso

Abstract

Small cell carcinoma represents 20% of lung cancers, rarely occurs in other sites. Extrapulmonary small cell carcinoma is aggressive with a propensity for regional and distant dissemination. This type of carcinoma is a rare neoplasm in the breast. Although the clinical appearance is nonspecific, it often responds well to therapy and has a good prognosis of survival. We present the case of a 50-year-old woman with extrapulmonary small cell carcinoma of the breast. Physical examination showed a lesion of 4 x 3 x 3 centimeters confirmed by magnetic resonance imaging of left breast. Diagnosis was made by a core biopsy that showed the characteristics of small, round, lymphocyte-like cells with hyperchromatic nuclei and scarce cytoplasm compatible with small cell carcinoma of the breast. Patient was treated with chemotherapy before undergoing total mastectomy and resection of the lymph nodes. Keywords: Breast, Breast carcinoma, Extrapulmonary small cell carcinoma, Small cell cancer