Research progress of medical nitric oxide production technology

Qian Li, Wenlu Zhang, Hong Wang, Yan Wang
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Abstract

Nitric oxide is a messenger molecule in the body, which is widely distributed in various tissues of living organisms and participates in regulating the physiological activities of cells. Inhalation of low concentrations of NO can selectively relax the pulmonary blood vessels, which can achieve good results and has been applied in clinical respiratory emergency treatment such as pulmonary hypertension, neonatal hypoxic respiratory failure, acute respiratory distress syndrome (ARDS), etc. At present, in addition to the clinical use of chemical methods to produce NO gas (storage in cylinders), NO can also be generated by discharge. Among them, the pulsed arc discharge can realize the preparation of NO at any time and solve the problems of decompression and storage of conventional NO gas supply. In this paper, the clinical application of NO, discharge technology, and removal methods of nitrogen dioxide (NO2) were reviewed. Key words: Nitric oxide; Pulse discharge; Plasma; Preparation; Catalyticreduction
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医用一氧化氮生产技术研究进展
一氧化氮是体内的信使分子,广泛分布于生物体的各种组织中,参与调节细胞的生理活动。吸入低浓度NO可选择性舒张肺血管,可取得良好效果,已应用于肺动脉高压、新生儿缺氧性呼吸衰竭、急性呼吸窘迫综合征(ARDS)等临床呼吸急救,除了临床上使用化学方法产生NO气体(储存在气瓶中)外,还可以通过放电产生NO。其中,脉冲电弧放电可以实现NO的随时制备,解决了传统NO气源的减压和储存问题。本文综述了一氧化氮的临床应用、排放技术和二氧化氮的去除方法。关键词:一氧化氮;脉冲放电;等离子体;准备工作;催化还原
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