{"title":"An Overview about the Relationship between Cystatin C and Inflammatory Diseases","authors":"Yixin Huang","doi":"10.26420/austinjanalpharmchem.2022.1152","DOIUrl":null,"url":null,"abstract":"Cystatin C (Cys-C) is a protease inhibitor that can be produced by nuclear cells in the human body. Its principal function is to inhibit the activity of various cysteine proteases in vivo. In addition, Cys-C also plays an essential role in regulating antigen presentation, extracellular matrix degradation, and the balance of protein production and decomposition in living cells. Cys-C is involved in the pathophysiological processes of chronic inflammatory diseases, including cardiovascular, cerebrovascular, and respiratory diseases. This article reviews the effects of Cys-C on chronic inflammatory diseases and its therapeutic prospects.","PeriodicalId":91055,"journal":{"name":"Austin journal of analytical and pharmaceutical chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Austin journal of analytical and pharmaceutical chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26420/austinjanalpharmchem.2022.1152","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Cystatin C (Cys-C) is a protease inhibitor that can be produced by nuclear cells in the human body. Its principal function is to inhibit the activity of various cysteine proteases in vivo. In addition, Cys-C also plays an essential role in regulating antigen presentation, extracellular matrix degradation, and the balance of protein production and decomposition in living cells. Cys-C is involved in the pathophysiological processes of chronic inflammatory diseases, including cardiovascular, cerebrovascular, and respiratory diseases. This article reviews the effects of Cys-C on chronic inflammatory diseases and its therapeutic prospects.
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