Application of PSMA ligands PET imaging in the diagnosis and treatment of non-prostate tumors

Guanyun Wang, Peng Yu, Jing Ning, Baixuan Xu
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Abstract

Prostate specific membrane antigen (PSMA) is a hot topic in molecular imaging research of prostate cancer. However, non-prostate related PSMA can also be expressed in physiological tissues and different benign and malignant diseases, especially in tumor-associated endovascular endothelial cells. Related clinical studies have demonstrated the staging potential of PSMA ligands PET imaging in non-prostate tumors. This article summarizes the application of PSMA ligands PET imaging in the diagnosis and treatment of non-prostate tumors. Key words: Prostate-specific membrane antigen; Positron-emission tomography; Trends
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PSMA配体PET显像在非前列腺肿瘤诊断和治疗中的应用
前列腺特异性膜抗原(PSMA)是癌症分子影像学研究的热点。然而,非前列腺相关的PSMA也可以在生理组织和不同的良性和恶性疾病中表达,尤其是在肿瘤相关的血管内内皮细胞中。相关临床研究已经证明PSMA配体PET成像在非前列腺肿瘤中的分期潜力。本文综述了PSMA配体PET显像在非前列腺肿瘤诊断和治疗中的应用。关键词:前列腺特异性膜抗原;正电子发射断层扫描;趋势
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来源期刊
中华核医学与分子影像杂志
中华核医学与分子影像杂志 核医学,分子影像
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5088
期刊介绍: Chinese Journal of Nuclear Medicine and Molecular Imaging (CJNMMI) was established in 1981, with the name of Chinese Journal of Nuclear Medicine, and renamed in 2012. As the specialized periodical in the domain of nuclear medicine in China, the aim of Chinese Journal of Nuclear Medicine and Molecular Imaging is to develop nuclear medicine sciences, push forward nuclear medicine education and basic construction, foster qualified personnel training and academic exchanges, and popularize related knowledge and raising public awareness. Topics of interest for Chinese Journal of Nuclear Medicine and Molecular Imaging include: -Research and commentary on nuclear medicine and molecular imaging with significant implications for disease diagnosis and treatment -Investigative studies of heart, brain imaging and tumor positioning -Perspectives and reviews on research topics that discuss the implications of findings from the basic science and clinical practice of nuclear medicine and molecular imaging - Nuclear medicine education and personnel training - Topics of interest for nuclear medicine and molecular imaging include subject coverage diseases such as cardiovascular diseases, cancer, Alzheimer’s disease, and Parkinson’s disease, and also radionuclide therapy, radiomics, molecular probes and related translational research.
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