Multiple pulmonary hyalinizing granulomas mimicking widespread lung metastasis

Abstract

Pulmonary hyalinizing granuloma (PHG) is a rare benign lesion that can be unilaterally or bilaterally presented in the form of solitary or multiple nodules and masses. It may also be related to mediastinal and retroperitoneal fibrosis, autoimmune diseases, tumors, or infectious diseases. The definitive diagnosis of PHG can only be made by pathological evaluation. A 64-year-old male applied to the hospital to undergo an inguinal hernia repair operation. Preoperative chest imaging revealed multiple pulmonary nodules with lobulated contours and regular margins scattered throughout both lungs. Pathologic evaluation revealed that nodules were consistent with PHG. In addition, soft-tissue density observed around the abdominal aorta was compatible with retroperitoneal fibrosis, which may accompany this disease.