A case of lower limbs infection caused by Helcococcus Kunzii and literature analysis

Abstract

Objective To describe a case of lower limbs infection of Helcococcus Kunzii in North China University of Science and Technology Affiliated Hospital in October 2017 and to analyze the etiology and drug susceptibility. Methods The bacteria were identified by French Meriere mass spectrometer and BD Phoenix-100 automatic bacterial identification/drug sensitivity system.The drug resistance of the bacteria was detected by disk diffusion method, and collected the clinical information and related literature information of the Helcococcus Kunzi to analyze. Results The Gram-positive cocci was isolated from the foot secretion of a patient with venous thrombosis of lower limbs complicated with infection.The result of smear was Gram-positive cocci in double, agglomerate and varied in size.On the blood plate, there was a small colony of α hemolysis.Thixozyme negative, β galactosidase negative.The results of mass spectrometry identification and two kinds of fully automatic bacterial identification / drug sensitivity system were identified as Helcococcus Kunzii, the isolates was resistant to erythromycin and clindamycin among the 10 antibiotics tested.By searching, sorting out and analyzing the literature information, it is revealed that the infection of this bacterium is not related to sex.Middle-aged and elderly people are mostly infected.And the cocci easily infected patients with lower immunity.The infection of lower limbs is 47.37%, the infection of blood flow is 15.79% and the other ways of infection are 42.11% (lung, mammary gland, etc.). Conclusion Helcococcus Kunzii is a conditional pathogen, and patients with lower immunity are more common.Erythromycin resistance could identify it from the green balloon bacteria.Moreover, the bacteria could cause a wide spectrum of diseases, and easily cause sepsis and lower limbs infections, which reminds us that we should be vigilant in clinical practice. Key words: Helcococcus Kunzii; Lower limb infection; Mass spectrometry identification; Drug resistance detection