Mineralizing Angiopathy: An Uncommon Cause of Pediatric Stroke with Good Outcomes

Abstract

ing trivial head trauma is very rare. We report a toddler who presented with right hemiparesis and had an acute infarct in the left basal ganglia. The infarct occurred in association with mineralization of the corresponding lenticulostriate arteries (LSAs), visualized as punctate calcifications on computed tomography (CT) of the brain. This condition represents a benign cause of pediatric stroke, known as mineralizing angiopathy [1]. A previously healthy, 30-month-old male child presented with paucity of movements in the right upper and lower limbs, as well as deviation of the mouth angle towards the left side, noted after a time lag of 30 minutes following a fall from a bed. Examination revealed poor anti-gravity movements of the right upper and lower limbs with decreased tone and depressed muscle stretch reflexes on the right side, along with rightside upper motor neuron facial nerve palsy. Brain magnetic resonance imaging (MRI) showed an acute infarct in the left lentiform nucleus and internal capsule with diffusion restriction and hyperintensity in the fluid attenuated inversion recovery sequence. An MRI angiogram did not reveal any occlusion of the vessels. Brain CT revealed calcifications in the bilateral basal ganglia in the distribution of the LSA (Fig. 1). A pISSN 2635-909X • eISSN 2635-9103 Ann Child Neurol [Epub ahead of print] https://doi.org/10.26815/acn.2021.00521