{"title":"Clinical case of indolent primary medullary cancer","authors":"S. Miroshnikov, D. B. Demin, A. Belyaeva","doi":"10.14341/serg12713","DOIUrl":null,"url":null,"abstract":"Medullary thyroid cancer (MRSH) has a high malignant potential in the vast majority of cases, but in some patients with MRSH is characterized by a sluggish, non-aggressive course, when patients with the presence of proven medullary carcinoma or distant metastases and / or relapse, can live without progression for a sufficiently long time. Such a course of a malignant tumor is called indolent. The article presents a clinical case of diagnosis and treatment of indolent primary MRSH in a patient with a duration of the disease of 11 years. Shows some features of the dynamics of the level of basal calcitonin and cancer-embryonic antigen (CEA), ultrasound characteristics and data of fine-needle puncture biopsy of the tumor. The phenomenon of indolent course of MRSH characterized, as a rule, by a high malignant potential, is probably due to the biological characteristics of the tumor and requires further research.","PeriodicalId":30783,"journal":{"name":"Endokrinnaia khirurgiia","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Endokrinnaia khirurgiia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14341/serg12713","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Medullary thyroid cancer (MRSH) has a high malignant potential in the vast majority of cases, but in some patients with MRSH is characterized by a sluggish, non-aggressive course, when patients with the presence of proven medullary carcinoma or distant metastases and / or relapse, can live without progression for a sufficiently long time. Such a course of a malignant tumor is called indolent. The article presents a clinical case of diagnosis and treatment of indolent primary MRSH in a patient with a duration of the disease of 11 years. Shows some features of the dynamics of the level of basal calcitonin and cancer-embryonic antigen (CEA), ultrasound characteristics and data of fine-needle puncture biopsy of the tumor. The phenomenon of indolent course of MRSH characterized, as a rule, by a high malignant potential, is probably due to the biological characteristics of the tumor and requires further research.