Clinical case of indolent primary medullary cancer

S. Miroshnikov, D. B. Demin, A. Belyaeva
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Abstract

Medullary thyroid cancer (MRSH) has a high malignant potential in the vast majority of cases, but in some patients with MRSH is characterized by a sluggish, non-aggressive course, when patients with the presence of proven medullary carcinoma or distant metastases and / or relapse, can live without progression for a sufficiently long time. Such a course of a malignant tumor is called indolent. The article presents a clinical case of diagnosis and treatment of indolent primary MRSH in a patient with a duration of the disease of 11 years. Shows some features of the dynamics of the level of basal calcitonin and cancer-embryonic antigen (CEA), ultrasound characteristics and data of fine-needle puncture biopsy of the tumor. The phenomenon of indolent course of MRSH characterized, as a rule, by a high malignant potential, is probably due to the biological characteristics of the tumor and requires further research.
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惰性原发性癌症临床分析
甲状腺髓样癌(MRSH)在绝大多数病例中具有很高的恶性潜能,但在一些MRSH患者中,其特点是病程缓慢,非侵袭性,当患者存在髓样癌或远处转移和/或复发时,可以在足够长的时间内无进展。恶性肿瘤的这种病程称为惰性期。本文提出了一个临床病例的诊断和治疗的惰性原发性MRSH患者的病程为11年。显示肿瘤基础降钙素和癌胚抗原(CEA)水平的动态变化、超声特征和细针穿刺活检资料。MRSH的惰性病程通常具有较高的恶性潜能,这可能与肿瘤的生物学特性有关,需要进一步研究。
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审稿时长
6 weeks
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