M. Yu. Yukina, A. R. Elfimova, E. A. Troshina, G. A. Melnichenko, N. G. Mokrysheva
BACKGROUND : Currently, there are no data on the prevalence and incidence of insulinoma in Russia. The published world data on the epidemiology of the tumor are largely variable. Thus, it is important to systematize information on the prevalence and incidence of insulinoma in the world, including in Russia. AIM: To assess the prevalence and incidence of insulinoma in the world. TASKS Analysis of literature data. Analysis of the database of the Endocrinology Research Centre. MATERIALS AND METHODS : To implement Task 1, an analysis of foreign and Russian articles published in the PubMed and eLIBRARY.RU databases from 1927 was carried out until June 1, 2023, including the following keywords: «Insulinoma», «Epidemiology», «Frequency», «Incidence», «Nationwide», «Database». Based on the obtained results, an analysis of the prevalence and incidence of insulinoma in the world and in Russia was made. To implement Task 2, the analysis of patient records and the electronic database of the Endocrinology Research Centre was carried out. RESULTS : Based on data in individual countries the prevalence and incidence of insulinoma for the world population amounted to: an average of 16.4 per 1 million population and 0.9 per 1 million population per year, respectively. If extrapolating the world data, the number of patients with insulinoma in Russia can be 1066–2362 and 72–173 new cases are diagnosed annually (11.9 per 1 million population and 0.9 per 1 million population per year, respectively). The largest number of patients with insulinoma in Russia was recorded in the Endocrinology Research Centre and amounted to 275 cases for the period 2006–2022. CONCLUSION: In the Russian Federation, it is important to create a register of patients with insulinoma on the basis of the existing electronic database of the Endocrinology Research Centre in order to obtain accurate information about the current needs of patients with insulinoma in medical care and drug provision, as well as to conduct full-fledged scientific research.
{"title":"Insulinoma: analysis of prevalence and incidence in the world","authors":"M. Yu. Yukina, A. R. Elfimova, E. A. Troshina, G. A. Melnichenko, N. G. Mokrysheva","doi":"10.14341/serg12805","DOIUrl":"https://doi.org/10.14341/serg12805","url":null,"abstract":"BACKGROUND : Currently, there are no data on the prevalence and incidence of insulinoma in Russia. The published world data on the epidemiology of the tumor are largely variable. Thus, it is important to systematize information on the prevalence and incidence of insulinoma in the world, including in Russia. AIM: To assess the prevalence and incidence of insulinoma in the world. TASKS Analysis of literature data. Analysis of the database of the Endocrinology Research Centre. MATERIALS AND METHODS : To implement Task 1, an analysis of foreign and Russian articles published in the PubMed and eLIBRARY.RU databases from 1927 was carried out until June 1, 2023, including the following keywords: «Insulinoma», «Epidemiology», «Frequency», «Incidence», «Nationwide», «Database». Based on the obtained results, an analysis of the prevalence and incidence of insulinoma in the world and in Russia was made. To implement Task 2, the analysis of patient records and the electronic database of the Endocrinology Research Centre was carried out. RESULTS : Based on data in individual countries the prevalence and incidence of insulinoma for the world population amounted to: an average of 16.4 per 1 million population and 0.9 per 1 million population per year, respectively. If extrapolating the world data, the number of patients with insulinoma in Russia can be 1066–2362 and 72–173 new cases are diagnosed annually (11.9 per 1 million population and 0.9 per 1 million population per year, respectively). The largest number of patients with insulinoma in Russia was recorded in the Endocrinology Research Centre and amounted to 275 cases for the period 2006–2022. CONCLUSION: In the Russian Federation, it is important to create a register of patients with insulinoma on the basis of the existing electronic database of the Endocrinology Research Centre in order to obtain accurate information about the current needs of patients with insulinoma in medical care and drug provision, as well as to conduct full-fledged scientific research.","PeriodicalId":30783,"journal":{"name":"Endokrinnaia khirurgiia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136337779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"To the 120th anniversary of the birth of Professor Oleg Vladimirovich Nikolaev (1903–1980)","authors":"I. V. Kim, N. Nuralieva","doi":"10.14341/serg12801","DOIUrl":"https://doi.org/10.14341/serg12801","url":null,"abstract":"<jats:p>.</jats:p>","PeriodicalId":30783,"journal":{"name":"Endokrinnaia khirurgiia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49278182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In memory of Bondarenko Vladimir Olegovich (07.06.1960–15.08.2022)","authors":"I. V. Kim","doi":"10.14341/serg12802","DOIUrl":"https://doi.org/10.14341/serg12802","url":null,"abstract":"<jats:p>.</jats:p>","PeriodicalId":30783,"journal":{"name":"Endokrinnaia khirurgiia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45324556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
U. V. Buyvalenko, M. S. Sheremeta, I. V. Kim, A. A. Trukhin, M. O. Korchagina, N. Yu. Sviridenko
Thyroid functional autonomy (TFA) is the most frequent reasons of subclinical or manifest thyrotoxicosis. Diagnosis of the causes of thyrotoxicosis (destruction or increased functional activity of the thyroid tissue in nodular and diffuse thyroid pathology) is a key point in determining the management of patients with this pathology. Scintigraphy is the method of choice in differential diagnosis of the causes of thyrotoxicosis assessing the functional state of the thyroid gland. Thyroid scintigraphy can be performed using 99mTc-pertechnetate. After normalization of the level of thyroid hormones is confirmed, radical treatment is recommended. It could be surgery or radioactive iodine therapy (RAI). In some cases, especially in the elderly women, TFA is combined with thyroid nodules (TN), which can cause pressure symptoms, cosmetic complaints, and thyroid dysfunction. Minimally invasive treatments, such as percutaneous ethanol injection (PEI) sclerotherapy, has been proposed, especially for pressure symptoms and cosmetic complaints, as an alternative to surgery. The presented clinical case will demonstrate the possibility of use sclerotherapy and RAI for the successful treatment of TFA with TN.
{"title":"Thyroid functional autonomy — sclerotherapy and radioactive iodine therapy: case report","authors":"U. V. Buyvalenko, M. S. Sheremeta, I. V. Kim, A. A. Trukhin, M. O. Korchagina, N. Yu. Sviridenko","doi":"10.14341/serg12737","DOIUrl":"https://doi.org/10.14341/serg12737","url":null,"abstract":"Thyroid functional autonomy (TFA) is the most frequent reasons of subclinical or manifest thyrotoxicosis. Diagnosis of the causes of thyrotoxicosis (destruction or increased functional activity of the thyroid tissue in nodular and diffuse thyroid pathology) is a key point in determining the management of patients with this pathology. Scintigraphy is the method of choice in differential diagnosis of the causes of thyrotoxicosis assessing the functional state of the thyroid gland. Thyroid scintigraphy can be performed using 99mTc-pertechnetate. After normalization of the level of thyroid hormones is confirmed, radical treatment is recommended. It could be surgery or radioactive iodine therapy (RAI). In some cases, especially in the elderly women, TFA is combined with thyroid nodules (TN), which can cause pressure symptoms, cosmetic complaints, and thyroid dysfunction. Minimally invasive treatments, such as percutaneous ethanol injection (PEI) sclerotherapy, has been proposed, especially for pressure symptoms and cosmetic complaints, as an alternative to surgery. The presented clinical case will demonstrate the possibility of use sclerotherapy and RAI for the successful treatment of TFA with TN.","PeriodicalId":30783,"journal":{"name":"Endokrinnaia khirurgiia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135215403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BACKGROUND : the main reason for postoperative vocal folds paresis is the variable anatomy of the recurrent laryngeal nerve. An example of such an “extreme form of embryonal development» is the non-recurrent laryngeal nerve. However, many surgeons consider this structure to be a rare anomaly with prevalence less than 0.5%. This opinion is associated with a six to seven-fold increase in the number of vocal folds paresis when a surgeon encounters with a non-recurrent laryngeal nerve. Meanwhile, in cadaveric studies a significantly higher prevalence of non-recurrent laryngeal nerve was demonstrated — 2.2%. The right aberrant subclavian artery was diagnosed during CT in 3.1% patients. AIM : the aim of the study is to determine the effectiveness of preoperative ultrasound in detecting the right aberrant subclavian artery and non-recurrent laryngeal nerve. MATERIALS AND METHODS : patients underwent thyroid and parathyroid surgery with identification of a right inferior laryngeal nerve. The preoperative neck ultrasound was performed on all patients with visualization of a brachiocephalic trunk (Y-sign) or a right aberrant subclavian artery (AL-sign). CT-angiography was performed in the postoperative period on patients who had a non-recurrent laryngeal nerve. RESULTS : the study included 1476 patients. The Y-sign was determined among 1338 (90.7%) patients. In these cases a typical anatomy of the recurrent laryngeal nerve was observed. In 138 (9.3%) cases, the Y-sign was not detected. In this subgroup of patients, in 20 (1.4%) cases, a non-recurrent laryngeal nerve and a right aberrant subclavian artery were noted. Thus, the sensitivity of the Y-sign in confirming the normal anatomy of the recurrent laryngeal nerve was 100%, specificity — 91.9%, positive prognostic value — 14.5%, negative prognostic value — 100%. On the contrary, AL-sign was notedall 20 (1.4%) patients with non-recurrent laryngeal nerve and right aberrant subclavian artery. False positive and false negative results were not observed. Three variants of the non-recurrent laryngeal nerve were identified: type I (superior type) — located behind the upper third of the thyroid lobe, has a direct descending way and forms an angle to the larynx of 30–50°; type III (inferior type) — has a direct ascending way (simulates the course of the recurrent laryngeal nerve) and forms an angle to trachea in 30–50°; type II (middle type) — all variants of the non-recurrent laryngeal nerve located between types I and III. CONCLUSION : the preoperative ultrasound detection of brachiocephalic trunk (Y-sign) confirms the presence of a recurrent laryngeal nerve (sensitivity 100%), and visualization of the right aberrant subclavian artery (AL-sign) determines a non-recurrent laryngeal nerve (sensitivity and specificity 100%).
{"title":"Non-recurrent laryngeal nerve in thyroid and parathyroid surgery","authors":"A. A. Kuprin, N. N. Vetsheva, I. O. Abuladze","doi":"10.14341/serg12788","DOIUrl":"https://doi.org/10.14341/serg12788","url":null,"abstract":"BACKGROUND : the main reason for postoperative vocal folds paresis is the variable anatomy of the recurrent laryngeal nerve. An example of such an “extreme form of embryonal development» is the non-recurrent laryngeal nerve. However, many surgeons consider this structure to be a rare anomaly with prevalence less than 0.5%. This opinion is associated with a six to seven-fold increase in the number of vocal folds paresis when a surgeon encounters with a non-recurrent laryngeal nerve. Meanwhile, in cadaveric studies a significantly higher prevalence of non-recurrent laryngeal nerve was demonstrated — 2.2%. The right aberrant subclavian artery was diagnosed during CT in 3.1% patients. AIM : the aim of the study is to determine the effectiveness of preoperative ultrasound in detecting the right aberrant subclavian artery and non-recurrent laryngeal nerve. MATERIALS AND METHODS : patients underwent thyroid and parathyroid surgery with identification of a right inferior laryngeal nerve. The preoperative neck ultrasound was performed on all patients with visualization of a brachiocephalic trunk (Y-sign) or a right aberrant subclavian artery (AL-sign). CT-angiography was performed in the postoperative period on patients who had a non-recurrent laryngeal nerve. RESULTS : the study included 1476 patients. The Y-sign was determined among 1338 (90.7%) patients. In these cases a typical anatomy of the recurrent laryngeal nerve was observed. In 138 (9.3%) cases, the Y-sign was not detected. In this subgroup of patients, in 20 (1.4%) cases, a non-recurrent laryngeal nerve and a right aberrant subclavian artery were noted. Thus, the sensitivity of the Y-sign in confirming the normal anatomy of the recurrent laryngeal nerve was 100%, specificity — 91.9%, positive prognostic value — 14.5%, negative prognostic value — 100%. On the contrary, AL-sign was notedall 20 (1.4%) patients with non-recurrent laryngeal nerve and right aberrant subclavian artery. False positive and false negative results were not observed. Three variants of the non-recurrent laryngeal nerve were identified: type I (superior type) — located behind the upper third of the thyroid lobe, has a direct descending way and forms an angle to the larynx of 30–50°; type III (inferior type) — has a direct ascending way (simulates the course of the recurrent laryngeal nerve) and forms an angle to trachea in 30–50°; type II (middle type) — all variants of the non-recurrent laryngeal nerve located between types I and III. CONCLUSION : the preoperative ultrasound detection of brachiocephalic trunk (Y-sign) confirms the presence of a recurrent laryngeal nerve (sensitivity 100%), and visualization of the right aberrant subclavian artery (AL-sign) determines a non-recurrent laryngeal nerve (sensitivity and specificity 100%).","PeriodicalId":30783,"journal":{"name":"Endokrinnaia khirurgiia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135601643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. V. Sergiiko, D. V. Korotovskii, S. A. Lukyanov, O. G. Baturin, A. S. Butorin, T. E. Ilyina
We present a clinical case of a patient with metachronous primary multiple carcinoma of left kidney (2004) with left adrenal metastasis (2021), occult low-grade follicular thyroid carcinoma with lateral neck lymph node metastasis (2019), central lung cancer (2020), primary hyperparathyroidism with coherent parathyroid adenomas with intrathyroid and typical location. Patient had undergone left-side nephrectomy with bilateral adrenalectomy, double-staged thyroidectomy with parathyroidectomy and selective lateral neck dissection and right-side pulmonectomy with 4 sessions of chemotherapy. Almost 20 years after first operation patient has no signs of tumors recurrence. In addition, patient is undergoing hormone replacement therapy (HRT) of adrenal insufficiency and thyroid hormone suppression therapy. This case represents combination of non-hereditary endocrine neoplasms with multiple carcinomas. It also examples mistakes and difficulties of differential diagnosis of primary adrenal tumors and adrenal metastasis.
{"title":"Difficulties and missteps of diagnosis and surgical treatment of patient with multifocal metachronic carcinoma associated with primary hyperparathyroidism","authors":"S. V. Sergiiko, D. V. Korotovskii, S. A. Lukyanov, O. G. Baturin, A. S. Butorin, T. E. Ilyina","doi":"10.14341/serg12787","DOIUrl":"https://doi.org/10.14341/serg12787","url":null,"abstract":"We present a clinical case of a patient with metachronous primary multiple carcinoma of left kidney (2004) with left adrenal metastasis (2021), occult low-grade follicular thyroid carcinoma with lateral neck lymph node metastasis (2019), central lung cancer (2020), primary hyperparathyroidism with coherent parathyroid adenomas with intrathyroid and typical location. Patient had undergone left-side nephrectomy with bilateral adrenalectomy, double-staged thyroidectomy with parathyroidectomy and selective lateral neck dissection and right-side pulmonectomy with 4 sessions of chemotherapy. Almost 20 years after first operation patient has no signs of tumors recurrence. In addition, patient is undergoing hormone replacement therapy (HRT) of adrenal insufficiency and thyroid hormone suppression therapy. This case represents combination of non-hereditary endocrine neoplasms with multiple carcinomas. It also examples mistakes and difficulties of differential diagnosis of primary adrenal tumors and adrenal metastasis.","PeriodicalId":30783,"journal":{"name":"Endokrinnaia khirurgiia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136084743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. V. Semikova, S. Dora, Z. V. Shvets, E. A. Kulchitskaya, A. Volkova
BACKGROUND: Obesity is associated with development of menstrual disorders (MD), a decrease in ovarian reserve and infertility. Treatment of obesity contributes to the normalization of the reproductive function of women. Bariatric surgery is known to be the most effective method of obesity treatment, while the most common intervention is the sleeve gastrectomy (SG), the effect of which on menstrual function and ovarian reserve has not been studied enough.AIM: To study the effect of SG on menstrual function and ovarian reserve in obese women of reproductive ageMATERIALS AND METHODS: Female patients with BMI ≥ 35 kg/m2 aged 25 to 36 years were examined. At baseline and 6 months after SG, the characteristics of menstrual function were determined, BMI and HOMA-IR were calculated, and the level of anti-Müllerian hormone (AMH) was measured. The obtained parameters were compared in patients with and without MDRESULTS: . In all patients, 6 months after SG, there was a decrease in BMI: 30.1 kg/m2 (29.3–32.1) and 39.3 kg/m2 (37.3–41.0) (p<0.001), HOMA -IR: 5.0 (4.1–5.9) and 2.8 (2.1–3.2) (p=0.001). The initial level of AMH in patients with MD (n=12) was lower than in patients with normal menstrual function (n=10): 2.4 ng/ml (1.9–2.0) and 3.2 ng/ml (2.6–4.2), respectively (p=0.032). A significant increase in AMH levels occurred only in the group of patients with MD (p=0.04). MD remained only in 3 women.CONCLUSION: SG in patients of reproductive age with obesity is associated with the normalization of menstrual function and an increase in AMH, as well as a decrease in the degree of insulin resistance.
{"title":"Influence of sleeve gastrectomy on menstrual function and ovarian reserve in patients with obesity","authors":"G. V. Semikova, S. Dora, Z. V. Shvets, E. A. Kulchitskaya, A. Volkova","doi":"10.14341/serg12780","DOIUrl":"https://doi.org/10.14341/serg12780","url":null,"abstract":"BACKGROUND: Obesity is associated with development of menstrual disorders (MD), a decrease in ovarian reserve and infertility. Treatment of obesity contributes to the normalization of the reproductive function of women. Bariatric surgery is known to be the most effective method of obesity treatment, while the most common intervention is the sleeve gastrectomy (SG), the effect of which on menstrual function and ovarian reserve has not been studied enough.AIM: To study the effect of SG on menstrual function and ovarian reserve in obese women of reproductive ageMATERIALS AND METHODS: Female patients with BMI ≥ 35 kg/m2 aged 25 to 36 years were examined. At baseline and 6 months after SG, the characteristics of menstrual function were determined, BMI and HOMA-IR were calculated, and the level of anti-Müllerian hormone (AMH) was measured. The obtained parameters were compared in patients with and without MDRESULTS: . In all patients, 6 months after SG, there was a decrease in BMI: 30.1 kg/m2 (29.3–32.1) and 39.3 kg/m2 (37.3–41.0) (p<0.001), HOMA -IR: 5.0 (4.1–5.9) and 2.8 (2.1–3.2) (p=0.001). The initial level of AMH in patients with MD (n=12) was lower than in patients with normal menstrual function (n=10): 2.4 ng/ml (1.9–2.0) and 3.2 ng/ml (2.6–4.2), respectively (p=0.032). A significant increase in AMH levels occurred only in the group of patients with MD (p=0.04). MD remained only in 3 women.CONCLUSION: SG in patients of reproductive age with obesity is associated with the normalization of menstrual function and an increase in AMH, as well as a decrease in the degree of insulin resistance.","PeriodicalId":30783,"journal":{"name":"Endokrinnaia khirurgiia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42661047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From the editorial office","authors":"N. S. Kuznetsov","doi":"10.14341/serg12791","DOIUrl":"https://doi.org/10.14341/serg12791","url":null,"abstract":".","PeriodicalId":30783,"journal":{"name":"Endokrinnaia khirurgiia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135792798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Dedov, G. Melnichenko, N. Mokrysheva, E. Andreeva, M. Antsiferov, D. G. Beltsevich, E. Bibik, A. Gorbacheva, M. V. Degtyarev, L. V. Yeghshatyan, A. Eremkina, T. L. Karonova, I. V. Kim, J. Krupinova, I. Kryukova, N. Kuznetsov, S. V. Lukyanov, E. Mamedova, N. V. Markina, S. Mirnaya, E. Pigarova, L. Rozhinskaya, K. Slashchuk, I. Sleptsov, N. B. Chagai
The article presents a draft of clinical recommendations for the diagnosis and treatment of primary hyperparathyroidism in adult patients, which provides a modern examination algorithm, discusses the basic principles of laboratory, instrumental diagnostics and treatment approaches.
{"title":"Draft of clinical guidelines for the diagnosis and treatment of primary hyperparathyroidism in adult patients","authors":"I. Dedov, G. Melnichenko, N. Mokrysheva, E. Andreeva, M. Antsiferov, D. G. Beltsevich, E. Bibik, A. Gorbacheva, M. V. Degtyarev, L. V. Yeghshatyan, A. Eremkina, T. L. Karonova, I. V. Kim, J. Krupinova, I. Kryukova, N. Kuznetsov, S. V. Lukyanov, E. Mamedova, N. V. Markina, S. Mirnaya, E. Pigarova, L. Rozhinskaya, K. Slashchuk, I. Sleptsov, N. B. Chagai","doi":"10.14341/serg12790","DOIUrl":"https://doi.org/10.14341/serg12790","url":null,"abstract":"The article presents a draft of clinical recommendations for the diagnosis and treatment of primary hyperparathyroidism in adult patients, which provides a modern examination algorithm, discusses the basic principles of laboratory, instrumental diagnostics and treatment approaches.","PeriodicalId":30783,"journal":{"name":"Endokrinnaia khirurgiia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42801748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Severskaya, E. Choinzonov, I. Reshetov, S. A. Ivanov, A. Polyakov, M. Kropotov, A. Mudunov, V. Polkin, P. Isaev, A. Ilyin, D. G. Beltsevich, V. Vanushko, P. Rumyantsev, G. Melnichenko, Y. Alymov, I. S. Romanov, A. V. Ignatova, E. Borodavina, V. Krylov, A. Shurinov, Z. Radjabova, D. Kulbakin, A. Nevolskikh, A. Gevorkov, E. Khmelevsky, S. Kutukova, A. Guz, I. Sleptsov, R. Chernikov, A. Stepanova, N. Falaleeva, S. Podvyaznikov, N. Rubtsova, A. N. Rudyk, S. Musin, I. Gulidov, L. Vladimirova, T. Semiglazova, T. A. Aghababyan, E. Kostromina
The article presents a draft of clinical recommendations for the diagnosis and treatment of medullary thyroid cancer in adult patients, which provides a modern examination algorithm, discusses the basic principles of laboratory, instrumental diagnostics and treatment approaches.
{"title":"Draft of clinical guidelines for the diagnosis and treatment of medullary thyroid cancer in adult patients","authors":"N. Severskaya, E. Choinzonov, I. Reshetov, S. A. Ivanov, A. Polyakov, M. Kropotov, A. Mudunov, V. Polkin, P. Isaev, A. Ilyin, D. G. Beltsevich, V. Vanushko, P. Rumyantsev, G. Melnichenko, Y. Alymov, I. S. Romanov, A. V. Ignatova, E. Borodavina, V. Krylov, A. Shurinov, Z. Radjabova, D. Kulbakin, A. Nevolskikh, A. Gevorkov, E. Khmelevsky, S. Kutukova, A. Guz, I. Sleptsov, R. Chernikov, A. Stepanova, N. Falaleeva, S. Podvyaznikov, N. Rubtsova, A. N. Rudyk, S. Musin, I. Gulidov, L. Vladimirova, T. Semiglazova, T. A. Aghababyan, E. Kostromina","doi":"10.14341/serg12794","DOIUrl":"https://doi.org/10.14341/serg12794","url":null,"abstract":"The article presents a draft of clinical recommendations for the diagnosis and treatment of medullary thyroid cancer in adult patients, which provides a modern examination algorithm, discusses the basic principles of laboratory, instrumental diagnostics and treatment approaches.","PeriodicalId":30783,"journal":{"name":"Endokrinnaia khirurgiia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47166797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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